Eflornithine hydrochloride monohydrate (CAS 96020-91-6)
QUICK LINKS
Eflornithine hydrochloride monohydrate is a compound that is studied primarily for its mechanism of action as an irreversible inhibitor of ornithine decarboxylase (ODC), an enzyme involved in polyamine biosynthesis. This specific inhibition is of interest in biochemistry and cell biology, where researchers explore the role of polyamines in cell proliferation and differentiation. The compound′s ability to affect polyamine levels makes it a useful tool for studying the regulation of cell growth and programmed cell death, or apoptosis, in various cell models. Additionally, eflornithine hydrochloride monohydrate is investigated for its effects on the hair follicle growth cycle, providing insights into the processes governing hair follicle development and cycling. Its impact on other ODC-related pathways also garners attention, as these could have implications for understanding the broader metabolic consequences of altered polyamine synthesis.
Eflornithine hydrochloride monohydrate (CAS 96020-91-6) References
- Population pharmacokinetic modeling and deconvolution of enantioselective absorption of eflornithine in the rat. | Johansson, CC., et al. 2013. J Pharmacokinet Pharmacodyn. 40: 117-28. PMID: 23307171
- A simple and sensitive assay for eflornithine quantification in rat brain using pre-column derivatization and UPLC-MS/MS detection. | Yang, S., et al. 2015. Biomed Chromatogr. 29: 918-24. PMID: 25365958
- Laser treatment for female facial hirsutism: are quality-of-life benefits sustainable? | Roche, A., et al. 2016. Clin Exp Dermatol. 41: 248-52. PMID: 26620607
- Continuous flow strategies for using fluorinated greenhouse gases in fluoroalkylations. | Fu, WC., et al. 2021. Chem Soc Rev. 50: 7378-7394. PMID: 34018500
- Late-stage difluoromethylation: concepts, developments and perspective. | Sap, JBI., et al. 2021. Chem Soc Rev. 50: 8214-8247. PMID: 34075979
- Epilation and depilation in the genital area - motivation, methods, risks and recommendations from a dermatological point of view. | Mezin-Sarbu, E. and Wohlrab, J. 2023. J Dtsch Dermatol Ges. 21: 455-462. PMID: 36960835
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Eflornithine hydrochloride monohydrate, 100 mg | sc-482063 | 100 mg | $147.00 |