Date published: 2026-3-6

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EB-47 dihydrochloride (CAS 1190332-25-2)

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Alternate Names:
1-Piperazineacetamide,4-[1-(6-amino-9H-purin-9-yl)-1-deoxy-β-D-ribofuranuron]-N-(2,3-dihydro-1H-isoindol-4-yl)-1-one.2HCl.2H2O
Application:
EB-47 dihydrochloride dihydrate is a useful PARP-1 inhibitor for proteomics research
CAS Number:
1190332-25-2
Purity:
≥95%
Molecular Weight:
610.5
Molecular Formula:
C24H27N9O62HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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EB-47 dihydrochloride dihydrate is recognized as an exceptionally potent inhibitor of PARP-1, a protein for DNA repair processes. Its water-soluble nature enhances its applicability in various experimental applications, particularly in aqueous environments. By effectively blocking PARP-1 activity, EB-47 dihydrochloride dihydrate plays a significant role in modulating cellular responses to DNA damage, thereby influencing cell survival and adaptation mechanisms. This inhibition is particularly relevant in research models of oxidative stress, where EB-47 may act to exhibit cytoprotective effects. These properties make it an invaluable tool in the study of cellular mechanisms underpinning reperfusion injury and inflammation, offering insights into the cellular pathways affected by oxidative challenges and the potential for cellular recovery and protection.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

EB-47 dihydrochloride, 1 mg

sc-221574
1 mg
$62.00

EB-47 dihydrochloride, 5 mg

sc-221574A
5 mg
$240.00