Domiphen bromide (CAS 538-71-6)

Domiphen bromide, an organic quaternary ammonium compound, has gained significant attention in scientific research due to its potent antimicrobial properties and surfactant capabilities. Its mechanism of action primarily involves disrupting the integrity of bacterial cell membranes, leading to cell lysis and death. Domiphen bromide achieves this by interacting with the negatively charged phospholipid components of bacterial cell membranes, causing membrane destabilization and permeabilization. This disrupts essential cellular processes such as nutrient uptake, ion transport, and energy production, ultimately resulting in bacterial death. In research settings, Domiphen bromide has been widely utilized as a disinfectant and preservative in microbiological studies, particularly for the inhibition of bacterial growth in laboratory cultures and experimental setups. Additionally, its surfactant properties make it useful for solubilizing hydrophobic compounds and enhancing the stability of emulsions in various biochemical assays. Moreover, Domiphen bromide has shown potential applications in the development of antimicrobial coatings for medical devices and surfaces to prevent bacterial colonization and biofilm formation. Overall, the versatile antimicrobial and surfactant properties of Domiphen bromide make it a valuable tool in research for studying microbial biology, antimicrobial resistance, and biomedical applications.