Docosahexaenoyl glycine (CAS 132850-40-9)

Docosahexaenoyl glycine, recognized under CAS number 132850-40-9, is a fascinating bioactive lipid conjugate that combines docosahexaenoic acid (DHA), an omega-3 fatty acid well-known for its presence in fish oils and some marine algae, with the amino acid glycine. This compound is part of a group known as fatty acid amides and is particularly interesting due to its role in cellular signaling processes. In research, docosahexaenoyl glycine has been extensively studied for its ability to modulate signaling pathways that influence inflammation and cellular stress responses. The molecule acts through a variety of mechanisms, including the activation or inhibition of certain receptor-mediated pathways and the modulation of enzyme activities related to the metabolism of fatty acids and inflammatory mediators. Research involving docosahexaenoyl glycine often focuses on its interaction with receptors like G-protein coupled receptors (GPCRs), which are critical for many aspects of cell signaling. Through such interactions, this lipid derivative can potentially influence a wide range of cellular functions including those related to cell survival, proliferation, and response to external stimuli. These studies are crucial for elucidating the complex roles of fatty acid derivatives in cellular communication and regulation, offering insights into the complex web of metabolic and signaling pathways that maintain cellular homeostasis and response mechanisms.