Date published: 2026-4-26

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Djenkolic Acid (CAS 498-59-9)

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Alternate Names:
S,S′-Methylenedi-L-cysteine; L-Djenkolic acid
CAS Number:
498-59-9
Molecular Weight:
254.32
Molecular Formula:
C7H14N2O4S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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The exact operation mechanism of Djenkolic acid is still not completely understood. However, it′s hypothesized that the compound functions by linking to specific receptors on the cell surface and curtailing their activity. This activity inhibition is speculated to be responsible for Djenkolic acid′s anti-inflammatory, anti-tumor, and anti-oxidant activities.


Djenkolic Acid (CAS 498-59-9) References

  1. Association of carbon disulfide with plants in the family Fabaceae.  |  Piluk, J., et al. 2001. J Chem Ecol. 27: 1525-34. PMID: 11504042
  2. Modulation of chromium(VI) toxicity by organic and inorganic sulfur species in yeasts from industrial wastes.  |  Pepi, M. and Baldi, F. 1992. Biometals. 5: 179-85. PMID: 1421967
  3. Arabidopsis mutants in the C-S lyase of glucosinolate biosynthesis establish a critical role for indole-3-acetaldoxime in auxin homeostasis.  |  Mikkelsen, MD., et al. 2004. Plant J. 37: 770-7. PMID: 14871316
  4. The deamination of djenkolic acid in rats.  |  RERABEK, J. 1950. Experientia. 6: 304-5. PMID: 15435518
  5. The effects of seed quality and pipecolic and djenkolic acids on bruchid beetle infestation in water deficit-stressed Acacia trees.  |  Or, K. and Ward, D. 2004. J Chem Ecol. 30: 2297-307. PMID: 15672672
  6. Partial Purification and Characterization of Cystine Lyase from Cabbage (Brassica oleracea var capitata).  |  Hall, DI. and Smith, IK. 1983. Plant Physiol. 72: 654-8. PMID: 16663061
  7. The action of formaldehyde on the cystine disulphide linkages of wool: 2. The conversion of subfraction A of the combined cystine into combined lanthionine and djenkolic acid and subfraction B into combined thiazolidine-4-carboxylic acid.  |  Middlebrook, WR. and Phillips, H. 1947. Biochem J. 41: 218-23. PMID: 16748145
  8. Structural modeling of djenkolic acid with sulfur replaced by selenium and tellurium.  |  Melnikov, P., et al. 2014. Molecules. 19: 4847-56. PMID: 24747644
  9. Non-protein amino acids in Australian acacia seed: implications for food security and recommended processing methods to reduce djenkolic acid.  |  Boughton, BA., et al. 2015. Food Chem. 179: 109-15. PMID: 25722145
  10. The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells.  |  Heinecke, JW., et al. 1987. J Biol Chem. 262: 10098-103. PMID: 3038867
  11. Metabolism of sulfur-containing amino acids in the dermatophyte Microsporum gypseum. I. Neutral amino acids.  |  Kunert, J. 1985. J Basic Microbiol. 25: 29-37. PMID: 3998995
  12. Thiazolidine-4-carboxylic acid, a physiologic sulfhydryl antioxidant with potential value in geriatric medicine.  |  Weber, HU., et al. 1982. Arch Gerontol Geriatr. 1: 299-310. PMID: 6764606
  13. Potential role of the flavin-containing monooxygenases in the metabolism of endogenous compounds.  |  Elfarra, AA. 1995. Chem Biol Interact. 96: 47-55. PMID: 7720104
  14. Studies on djenkol bean poisoning (djenkolism) in experimental animals.  |  Areekul, S., et al. 1976. Southeast Asian J Trop Med Public Health. 7: 551-8. PMID: 828979

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Djenkolic Acid, 1 g

sc-485042
1 g
$200.00