Disopyramide Antibody (003): sc-66034

Disopyramide Antibody (003) is a mouse monoclonal IgG3 antibody that detects Disopyramide in non-species reactive samples by enzyme-linked immunosorbent assay (ELISA). Disopyramide plays a crucial role as a Class IA antiarrhythmic medication, primarily used to manage ventricular and supraventricular arrhythmias, particularly in patients recovering from heart attacks. Disopyramide stabilizes irregular heartbeats by directly interfering with the depolarization of the cardiac membrane, acting as a membrane-stabilizing agent. This mechanism is essential for maintaining normal heart rhythm, as Disopyramide shortens the sinus node recovery time and lengthens the effective refractory period of the atrium, while minimally affecting the effective refractory period of the atrioventricular node. Additionally, Disopyramide exhibits depressant actions on the heart akin to guanidine and possesses anticholinergic and local anesthetic properties, which can contribute to therapeutic effects. Side effects may include dizziness, fainting, dry mouth, and unusual tiredness during treatment. Anti-Disopyramide antibody (003) serves as an invaluable tool for researchers studying the pharmacological effects and mechanisms of this important antiarrhythmic agent.