Molecular structure of Dihydrocytochalasin B, CAS Number: 39156-67-7
Dihydrocytochalasin B (CAS 39156-67-7)
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Application:
Dihydrocytochalasin B is a cell morphology and motility and inducer
CAS Number:
39156-67-7
Purity:
>98%
Molecular Weight:
481.63
Molecular Formula:
C29H39NO5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Dihydrocytochalasin B, also known as Cytochalasin H2B, a mycotoxin from Aspergillus flavus, has been a key tool in cell biology for over 40 years due to its potent inhibition of actin polymerization, disrupting cellular functions. Used primarily to explore the effects of actin filament disruption on cell behavior, it provides insights into toxin impacts on cell biochemistry and physiology. By binding to actin monomers, Dihydrocytochalasin B impedes filament formation, offering a window into gene expression and cell signaling pathways, and can lead to cell death when normal actin dynamics are compromised.
Dihydrocytochalasin B (CAS 39156-67-7) References
- Regulation of growth, protein synthesis, and maturation of fetal bovine epiphyseal chondrocytes grown in high-density culture in the presence of ascorbic acid, retinoic acid, and dihydrocytochalasin B. | Freyria, AM., et al. 1999. J Cell Biochem. 76: 84-98. PMID: 10581003
- Dihydrocytochalasin B. Biological effects and binding to 3T3 cells. | Atlas, SJ. and Lin, S. 1978. J Cell Biol. 76: 360-70. PMID: 10605443
- Centrifugal and chromatographic analyses of tryptophan and tyrosine uptake by red blood cells and GLUT1 proteoliposomes with permeability estimates and observations on dihydrocytochalasin B. | Lagerquist Hägglund, C. and Lundahl, P. 2003. J Biochem Biophys Methods. 55: 127-40. PMID: 12628696
- Tetraploidization increases sensitivity to Aurora B kinase inhibition. | Marxer, M., et al. 2012. Cell Cycle. 11: 2567-77. PMID: 22722494
- Dihydrocytochalasin B promotes adipose conversion of 3T3 cells. | Pairault, J. and Lasnier, F. 1987. Biol Cell. 61: 149-54. PMID: 2965943
- Microfilament modification by dihydrocytochalasin B causes retinoic acid-modulated chondrocytes to reexpress the differentiated collagen phenotype without a change in shape. | Benya, PD., et al. 1988. J Cell Biol. 106: 161-70. PMID: 3276711
- Alterations in chondrocyte cytoskeletal architecture during phenotypic modulation by retinoic acid and dihydrocytochalasin B-induced reexpression. | Brown, PD. and Benya, PD. 1988. J Cell Biol. 106: 171-9. PMID: 3276712
- Membrane-cytoskeleton interactions and the regulation of chemotactic peptide-induced activation of human granulocytes: the effects of dihydrocytochalasin B. | Jesaitis, AJ., et al. 1985. J Cell Biochem. 27: 241-53. PMID: 3838753
- Effect of cytochalasin B and dihydrocytochalasin B on invasiveness of entero-invasive bacteria in HEp-2 cell cultures. | Bukholm, G. 1984. Acta Pathol Microbiol Immunol Scand B. 92: 145-9. PMID: 6385614
- Effects of cytochalasin B and dihydrocytochalasin B on calcium transport by intestinal absorptive cells. | Jande, SS. and Liskova-Kiar, M. 1981. Calcif Tissue Int. 33: 143-51. PMID: 6783271
- Delay of HeLa cell cleavage into interphase using dihydrocytochalasin B: retention of a postmitotic spindle and telophase disc correlates with synchronous cleavage recovery. | Martineau, SN., et al. 1995. J Cell Biol. 131: 191-205. PMID: 7559776
- Remodeling of the plasma membrane after stimulation of neutrophils with f-Met-Leu-Phe and dihydrocytochalasin B: identification of membrane subdomains containing NADPH oxidase activity. | Mukherjee, G., et al. 1994. J Leukoc Biol. 55: 685-94. PMID: 8195693
- Dihydrocytochalasin B enhances transforming growth factor-beta-induced reexpression of the differentiated chondrocyte phenotype without stimulation of collagen synthesis. | Benya, PD. and Padilla, SR. 1993. Exp Cell Res. 204: 268-77. PMID: 8440324
- Modulation of the junctional integrity by low or high concentrations of cytochalasin B and dihydrocytochalasin B is associated with distinct changes in F-actin and ZO-1. | Nybom, P. and Magnusson, KE. 1996. Biosci Rep. 16: 313-26. PMID: 8896790
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dihydrocytochalasin B, 1 mg | sc-202579 | 1 mg | $157.00 |