Dihydro-3-(3-pyridoyl)-2-(3H)-furanone (CAS 59578-61-9)

Dihydro-3-(3-pyridoyl)-2-(3H)-furanone is an organic compound belonging to the oxolane class. In the realm of scientific research, Dihydro-3-(3-pyridoyl)-2-(3H)-furanone has been the subject of extensive study due to its significant biochemical and physiological effects. Numerous scientific research applications have utilized Dihydro-3-(3-pyridoyl)-2-(3H)-furanone as a valuable substrate in enzyme kinetic studies and as a reagent in organic synthesis. Its catalytic properties have also made it useful for the synthesis of various organic compounds, such as amides, esters, and nitriles. Furthermore, researchers have explored its potential in drug design and development, as it has displayed the ability to inhibit specific enzymes involved in drug metabolism. Particularly, Dihydro-3-(3-pyridoyl)-2-(3H)-furanone acts as an inhibitor of certain enzymes, specifically targeting cytochrome P450 3A4 (CYP3A4), an enzyme responsible for the metabolism of various drugs. The inhibition occurs through the formation of a covalent bond with the heme group of the enzyme, effectively preventing it from binding to its substrate.