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Dibutyltin diacetate is a catalyst that facilitates the esterification and transesterification reactions in organic synthesis. It acts by coordinating with the carbonyl oxygen of the carboxylic acid and alcohol, promoting the formation of the acyl intermediate. This coordination activates the carbonyl group, making it more susceptible to nucleophilic attack by the alcohol. The resulting tetrahedral intermediate collapses, leading to the formation of the ester product. Dibutyltin diacetate plays a role in promoting the reaction by facilitating the formation of the acyl intermediate and stabilizing the transition state, thereby increasing the rate of ester formation. Its mode of action involves the coordination of the tin atom with the carbonyl oxygen, which enhances the electrophilicity of the carbonyl carbon, ultimately leading to the desired ester product.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dibutyltin diacetate, 50 ml | sc-223935 | 50 ml | $61.00 | |||
Dibutyltin diacetate, 250 ml | sc-223935A | 250 ml | $184.00 |