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Dibenzepine HCl (CAS 315-80-0)

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Application:
Dibenzepine HCl is a tricyclic antidepressant antipsychotic small molecule
CAS Number:
315-80-0
Purity:
99%
Molecular Weight:
331.8
Molecular Formula:
C18H21N3O•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Dibenzepine HCl is a chemical compound utilized in research to study its role as an antagonist of muscarinic acetylcholine receptors. In the context of neuroscience research, it is applied to understand cholinergic signaling, which plays a significant role in cognitive functions and the autonomic nervous system. Dibenzepine HCl allows researchers to dissect the effects of muscarinic receptor inhibition on various physiological responses, including smooth muscle activity and glandular secretion. Moreover, the compound is instrumental in the exploration of the muscarinic pathways involved in central nervous system functions. By using Dibenzepine HCl in experimental models, scientists can investigate the complex interactions between neurotransmitters and their receptors, which is essential for a comprehensive understanding of both normal and altered neural physiology.


Dibenzepine HCl (CAS 315-80-0) References

  1. Nevirapine quantification in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry. Application to bioequivalence study.  |  Laurito, TL., et al. 2002. J Mass Spectrom. 37: 434-41. PMID: 11948850
  2. Determination of reboxetine, a recent antidepressant drug, in human plasma by means of two high-performance liquid chromatography methods.  |  Ragg, MA., et al. 2002. J Chromatogr A. 949: 23-33. PMID: 11999739
  3. Quantification of the HIV-integrase inhibitor raltegravir and detection of its main metabolite in human plasma, dried blood spots and peripheral blood mononuclear cell lysate by means of high-performance liquid chromatography tandem mass spectrometry.  |  Ter Heine, R., et al. 2009. J Pharm Biomed Anal. 49: 451-8. PMID: 19128911
  4. Effects of psychotropic drugs on methamphetamine-induced behavioral excitation in grouped mice.  |  Shintomi, K. 1975. Eur J Pharmacol. 31: 195-206. PMID: 238852
  5. Pregnancy influences the plasma pharmacokinetics but not the cerebrospinal fluid pharmacokinetics of raltegravir: a preclinical investigation.  |  Mahat, MY., et al. 2014. Eur J Pharm Sci. 65: 38-44. PMID: 25195836
  6. The effect of tricyclic antidepressants on ventricular fibrillation and collateral blood supply following acute coronary occlusion.  |  Manoach, M., et al. 1986. Heart Vessels. 2: 36-40. PMID: 2873124
  7. Magnesium fluxes in ventricular fibrillation and defibrillation in untreated and dibenzepine HC1 pretreated cats.  |  Stendig-Lindberg, G., et al. 1988. Magnes Res. 1: 45-50. PMID: 2908562
  8. Synthesis, crystal structure and biological activity of novel analogues of tricyclic drugs.  |  Bieszczad, B., et al. 2020. Bioorg Med Chem Lett. 30: 127493. PMID: 32798652
  9. Improved method for determining dibenzepine and its N-demethylated metabolites in human urine.  |  De Leenheer, A. and Heyndrickx, A. 1973. J Pharm Sci. 62: 31-6. PMID: 4716576
  10. The detection and determination of dibenzepine and its metabolites in autopsy material.  |  Brochon, R., et al. 1969. Arch Toxikol. 24: 249-59. PMID: 5795751
  11. Convulsive attacks due to antidepressant drug overdoses: case reports and discussion.  |  Flechter, S., et al. 1983. Gen Hosp Psychiatry. 5: 217-21. PMID: 6138296
  12. Replacement of (R)-methadone by a double dose of (R,S)-methadone in addicts: interindividual variability of the (R)/(S) ratios and evidence of adaptive changes in methadone pharmacokinetics.  |  Eap, CB., et al. 1996. Eur J Clin Pharmacol. 50: 385-9. PMID: 8839661

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dibenzepine HCl, 100 mg

sc-201115
100 mg
$153.00

Dibenzepine HCl, 500 mg

sc-201115A
500 mg
$306.00