Diazoacetyl-DL-norleucine methyl ester (CAS 7013-09-4)

Diazoacetyl-DL-norleucine methyl ester, or DANLE, is a synthetic derivative of the amino acid norleucine and has seen considerable interest for its potential applications in scientific investigation. Its ability to inhibit enzymes that play a role in protein synthesis has made it an important component in numerous laboratory tests. Diazoacetyl-DL-norleucine methyl ester′s unique properties have been explored in studies of protein synthesis in eukaryotic cells and in research examining the impact of protein synthesis inhibitors on cell growth and development. Diazoacetyl-DL-norleucine methyl ester also features in studies of gene expression and the effects of gene expression on cell growth and maturation. The exact mechanism through which Diazoacetyl-DL-norleucine methyl ester operates is not entirely known. Nonetheless, it′s thought that Diazoacetyl-DL-norleucine methyl ester hinders enzymes involved in protein synthesis by attaching itself to the enzyme′s active site, thereby preventing the substrate from binding. Furthermore, it′s suggested that Diazoacetyl-DL-norleucine methyl ester might interact with other enzymes engaged in protein synthesis, such as those participating in mRNA translation.