(DHQD)2PHAL (CAS 140853-10-7)
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(DHQD)2PHAL is a chiral ligand which is widely used in asymmetric synthesis research. This ligand is particularly valuable in the study of enantioselective catalysis, where it forms complexes with various metals to catalyze reactions that produce chiral molecules with high selectivity. Its effectiveness in catalyzing a variety of reactions, including but not limited to, asymmetric epoxidation, Diels-Alder, and Michael addition reactions, makes it a compound of significant interest for improving industrial synthetic processes. Moreover, (DHQD)2PHAL is also used in mechanistic studies to understand the fundamental principles of chirality and its influence on reaction pathways and outcomes. This ligand′s role in advancing the field of green chemistry is also noted, as it aids in the creation of more environmentally benign processes by reducing the need for excess reagents and by-products.
(DHQD)2PHAL (CAS 140853-10-7) References
- Catalytic asymmetric dihydroxylation using phenoxyethoxymethyl-polystyrene (PEM)-based novel microencapsulated osmium tetroxide (PEM-MC OsO4). | Kobayashi, S., et al. 2001. Org Lett. 3: 2649-52. PMID: 11506600
- Osmium-catalyzed asymmetric dihydroxylation of olefins by H2O2; dual role of the cinchona alkaloid ligand. | Jonsson, SY., et al. 2001. Org Lett. 3: 3463-6. PMID: 11678683
- A trifunctional catalyst for one-pot synthesis of chiral diols via Heck coupling-N-oxidation-asymmetric dihydroxylation: application for the synthesis of diltiazem and taxol side chain. | Choudary, BM., et al. 2003. J Org Chem. 68: 1736-46. PMID: 12608786
- MTO and OsO4: an efficient catalytic couple for mild H2O2-based asymmetric dihydroxylation of olefins. | Jonsson, SY., et al. 2003. Chemistry. 9: 2783-8. PMID: 12866542
- Diastereoselective synthesis of all eight l-hexoses from L-ascorbic acid. | Ermolenko, L. and Sasaki, NA. 2006. J Org Chem. 71: 693-703. PMID: 16408982
- Chemoselective asymmetric N-allylic alkylation of indoles with Morita-Baylis-Hillman carbonates. | Cui, HL., et al. 2009. Angew Chem Int Ed Engl. 48: 5737-40. PMID: 19554585
- Enantioselective, desymmetrizing bromolactonization of alkynes. | Wilking, M., et al. 2013. J Am Chem Soc. 135: 8133-6. PMID: 23679927
- Enantioselective chlorocyclization of indole derived benzamides for the synthesis of spiro-indolines. | Yin, Q. and You, SL. 2013. Org Lett. 15: 4266-9. PMID: 23909796
- Dissecting the stereocontrol elements of a catalytic asymmetric chlorolactonization: syn addition obviates bridging chloronium. | Yousefi, R., et al. 2013. J Am Chem Soc. 135: 14524-7. PMID: 24025085
- N-trifluoromethylthiophthalimide: a stable electrophilic SCF3 -reagent and its application in the catalytic asymmetric trifluoromethylsulfenylation. | Bootwicha, T., et al. 2013. Angew Chem Int Ed Engl. 52: 12856-9. PMID: 24123914
- Scalable solution-phase synthesis of the biologically active cyclodepsipeptide destruxin E, a potent negative regulator of osteoclast morphology. | Yoshida, M., et al. 2014. J Org Chem. 79: 296-306. PMID: 24251640
- Asymmetric chlorocyclization of indole-3-yl-benzamides for the construction of fused indolines. | Yin, Q. and You, SL. 2014. Org Lett. 16: 2426-9. PMID: 24730758
- Catalytic and highly enantioselective selenolactonization. | Niu, W. and Yeung, YY. 2015. Org Lett. 17: 1660-3. PMID: 25763679
- Diastereodivergent and Enantioselective [4+2] Annulations of γ-Butenolides with Cyclic 1-Azadienes. | Li, C., et al. 2015. Molecules. 20: 13642-58. PMID: 26225947
- Organocatalytic asymmetric chlorinative dearomatization of naphthols. | Yin, Q., et al. 2015. Chem Sci. 6: 4179-4183. PMID: 29218183
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(DHQD)2PHAL, 1 g | sc-239665 | 1 g | $140.00 |