Date published: 2025-10-15

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Defluoro Levofloxacin (CAS 117620-85-6)

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Alternate Names:
(3S)-2,3-Dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid;
Application:
Defluoro Levofloxacin is a nonfluorinated analog of Levofloxacin
CAS Number:
117620-85-6
Molecular Weight:
343.38
Molecular Formula:
C18H21N3O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Defluoro Levofloxacin is a chemical compound structurally related to the fluoroquinolone family, characterized by the absence of a fluorine atom typically present in related compounds. This structural modification significantly influences its chemical properties and interactions. Research into Defluoro Levofloxacin primarily revolves around its role as an intermediate in synthetic chemistry and its potential in studying the molecular mechanisms of fluoroquinolones. By modifying the fluoroquinolone core structure, researchers aim to understand how specific changes affect the behavior of these molecules at the molecular level, particularly in binding and interaction with various biological targets. In scientific studies, Defluoro Levofloxacin has been used to explore the dynamics of bacterial DNA gyrase and topoisomerase IV interactions. These enzymes are crucial for bacterial DNA replication and are common targets for antibacterial agents. By assessing how structural variations like the removal of the fluorine atom influence these interactions, scientists can gain insights into the design of more effective molecules with specific target site activity.


Defluoro Levofloxacin (CAS 117620-85-6) References

  1. Synthesis and biological testing of non-fluorinated analogues of levofloxacin.  |  Gray, JL., et al. 2003. Bioorg Med Chem Lett. 13: 2373-5. PMID: 12824037

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Defluoro Levofloxacin, 1 mg

sc-396769
1 mg
$360.00