De-N-sulfated heparin sodium salt (CAS 61932-66-9)

De-N-sulfated heparin sodium salt is a compound that functions as an anticoagulant by inhibiting the activity of thrombin and factor Xa. It achieves this by binding to antithrombin III, which enhances the inhibition of coagulation factors. De-N-sulfated heparin sodium salt exhibits anti-inflammatory properties by interacting with various cellular and molecular components involved in the inflammatory response. De-N-sulfated heparin sodium salt disrupts the interaction between selectins and their ligands, thereby reducing leukocyte recruitment and adhesion to the endothelium. It modulates the activity of chemokines and cytokines, leading to a decrease in the production of pro-inflammatory mediators. De-N-sulfated heparin sodium salt ′s mechanism of action involves interfering with the binding of growth factors to their receptors, thereby affecting cell proliferation and angiogenesis. De-N-sulfated heparin sodium salt exerts its function by inhibiting coagulation factors, modulating inflammatory responses, and interfering with cellular signaling pathways.