Date published: 2026-4-1

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Dapsone (CAS 80-08-0)

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Application:
Dapsone is a leukotriene B4 antagonist that inhibits LTB4 induced lysozyme release
CAS Number:
80-08-0
Purity:
≥97%
Molecular Weight:
248.30
Molecular Formula:
C12H12N2O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dapsone is a compound widely used in research applications, particularly due to its sulfone group, which is a point of interest in the study of chemical interactions and reactions. In the field of analytical chemistry, it often serves as a standard or reference compound in various chromatographic and spectroscopic methods, aiding in the identification and quantification of substances with similar structures. Researchers also explore the use of Dapsone in the synthesis of polymers and other advanced materials, as its molecular structure can potentially be incorporated into new compounds with unique physical and chemical properties. Its role in organic synthesis is significant, as it can undergo transformations that may yield insights into reaction mechanisms and the development of new synthetic methodologies. Additionally, Dapsone is used in environmental science to study the persistence and degradation of sulfone-containing compounds in various ecosystems.


Dapsone (CAS 80-08-0) References

  1. Inhibition of dapsone-induced methaemoglobinaemia by cimetidine in the presence of trimethoprim in the rat.  |  Coleman, MD., et al. 1992. J Pharm Pharmacol. 44: 114-8. PMID: 1352810
  2. The disposition of dapsone in cirrhosis.  |  May, DG., et al. 1992. Clin Pharmacol Ther. 51: 689-700. PMID: 1611807
  3. Double-blind placebo-controlled trial of dapsone in antihistamine refractory chronic idiopathic urticaria.  |  Morgan, M., et al. 2014. J Allergy Clin Immunol Pract. 2: 601-6. PMID: 25213055
  4. Dapsone for topical use in extemporaneous preparations.  |  Wohlrab, J. and Michael, J. 2018. J Dtsch Dermatol Ges. 16: 34-40. PMID: 29280553
  5. Dapsone for Pneumocystis jirovecii pneumonia prophylaxis - applying theory to clinical practice with a focus on drug interactions.  |  Corallo, CE., et al. 2020. Drug Metab Pers Ther. 35: PMID: 32681773
  6. Dapsone-induced methemoglobinemia in pediatrics post-renal transplant.  |  Hindka, A., et al. 2021. Pediatr Transplant. 25: e13921. PMID: 33280223
  7. Dapsone in the treatment of cutaneous lupus erythematosus.  |  Lindskov, R. and Reymann, F. 1986. Dermatologica. 172: 214-7. PMID: 3519302
  8. Efficacy and safety of dapsone gel for acne: a systematic review and meta-analysis.  |  Wang, X., et al. 2022. Ann Palliat Med. 11: 611-620. PMID: 35249339
  9. A comprehensive insight into the anti-inflammatory properties of dapsone.  |  Khalilzadeh, M., et al. 2022. Naunyn Schmiedebergs Arch Pharmacol. 395: 1509-1523. PMID: 36125533
  10. Dapsone-induced neutropenia in patients treated for ocular cicatricial pemphigoid.  |  Raizman, MB., et al. 1994. Ophthalmology. 101: 1805-7. PMID: 7800360
  11. Dapsone-induced aplastic anemia in a woman with bullous systemic lupus erythematosus.  |  Meyerson, MA. and Cohen, PR. 1994. Mayo Clin Proc. 69: 1159-62. PMID: 7967777
  12. A dapsone-induced blood dyscrasia in the mouse: evidence for the role of an active metabolite.  |  Ahmadi, M., et al. 1996. J Pharm Pharmacol. 48: 228-32. PMID: 8935178
  13. Methemoglobinemia associated with dapsone treatment in solid organ transplant recipients: a two-case report and review.  |  Plotkin, JS., et al. 1997. Liver Transpl Surg. 3: 149-52. PMID: 9346728

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dapsone, 1 g

sc-203023
1 g
$19.00

Dapsone, 5 g

sc-203023A
5 g
$32.00