Date published: 2026-4-28

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D-Talono-1,4-Lactone (CAS 23666-11-7)

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Alternate Names:
D-Talonic Acid γ-Lactone
CAS Number:
23666-11-7
Molecular Weight:
178.14
Molecular Formula:
C6H10O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D-Talono-1,4-Lactone is a carbohydrate derivative known for its cyclic lactone structure, derived from D-talonic acid. It plays a significant role in carbohydrate research due to its structural resemblance to various monosaccharides and the lactone ring system that confers unique chemical properties. This compound is particularly useful in understanding the biochemical pathways involved in sugar metabolism and can serve as a model compound in studies related to carbohydrate chemistry. One of the principal research applications involves the exploration of enzymatic specificity and catalytic mechanisms. The lactone structure makes D-Talono-1,4-Lactone an ideal substrate to probe the activity of carbohydrate-active enzymes, particularly those involved in lactone hydrolysis. Understanding these mechanisms aids in mapping glycoside hydrolase specificity and kinetics. In synthetic organic chemistry, D-Talono-1,4-Lactone is also used to synthesize more complex carbohydrate derivatives. The reactive lactone ring allows for various chemical modifications, helping researchers develop and analyze glycoconjugates or novel carbohydrate structures. Additionally, this compound provides valuable insights into carbohydrate metabolism. It aids in tracking metabolic pathways where sugar lactones are intermediate products. Thus, D-Talono-1,4-Lactone serves as a vital tool in understanding the metabolism and enzymatic processing of complex carbohydrates.


D-Talono-1,4-Lactone (CAS 23666-11-7) References

  1. Discovery of an L-fucono-1,5-lactonase from cog3618 of the amidohydrolase superfamily.  |  Hobbs, ME., et al. 2013. Biochemistry. 52: 239-53. PMID: 23214453
  2. l-Galactose metabolism in Bacteroides vulgatus from the human gut microbiota.  |  Hobbs, ME., et al. 2014. Biochemistry. 53: 4661-70. PMID: 24963813

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-Talono-1,4-Lactone, 5 mg

sc-474492
5 mg
$300.00