Date published: 2026-4-25

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D-myo-Inositol-1,3,4-triphosphate sodium salt

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Alternate Names:
1,3,4-IP3 (sodium salt); Ins(1,3,4)-P3 (sodium salt)
Application:
D-myo-Inositol-1,3,4-triphosphate sodium salt is an inhibitor of Ins(3,4,5,6)-P4 kinase activity
Purity:
>98%
Molecular Weight:
486.04
Molecular Formula:
C6H12O15P33Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D-myo-Inositol-1,3,4-triphosphate sodium salt is an inositol phosphate derivative that serves as an important signaling molecule in cellular processes. As a tris-phosphorylated form of inositol, it plays a significant role in intracellular signal transduction pathways. This specific configuration of phosphate groups allows it to interact with various protein targets, modulating cellular processes like ion channel regulation and cytoskeletal organization. Its role in the inositol phosphate pathway is linked to the regulation of calcium homeostasis, where it influences the release of calcium from intracellular stores, thereby impacting cellular activities like exocytosis, muscle contraction, and cell proliferation. In research, D-myo-Inositol-1,3,4-triphosphate sodium salt is employed to study the signaling networks of inositol phosphates. Researchers use this molecule to investigate the regulation and specificity of protein binding, particularly with kinases, phosphatases, and other proteins involved in calcium signaling. Its modulation of intracellular calcium levels provides insights into complex signaling mechanisms governing immune responses and cellular growth. By using this compound, scientists can uncover more about the cellular cross-talk between different inositol phosphates and protein interactions, helping explain the fine-tuned regulatory mechanisms of various biological processes.


D-myo-Inositol-1,3,4-triphosphate sodium salt References

  1. Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate.  |  Yang, X., et al. 1999. J Biol Chem. 274: 18973-80. PMID: 10383396
  2. Inositol phosphate biochemistry.  |  Majerus, PW. 1992. Annu Rev Biochem. 61: 225-50. PMID: 1323235
  3. The role of cytosolic free calcium in the generation of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate in HL-60 cells. Differential effects of chemotactic peptide receptor stimulation at distinct Ca2+ levels.  |  Lew, PD., et al. 1986. J Biol Chem. 261: 13121-7. PMID: 3489712
  4. Inositol trisphosphate and calcium signalling.  |  Berridge, MJ. 1993. Nature. 361: 315-25. PMID: 8381210
  5. Structure and function of inositol 1,4,5-trisphosphate receptor.  |  Yoshida, Y. and Imai, S. 1997. Jpn J Pharmacol. 74: 125-37. PMID: 9243320

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-myo-Inositol-1,3,4-triphosphate sodium salt, 100 µg

sc-223919
100 µg
$88.00

D-myo-Inositol-1,3,4-triphosphate sodium salt, 500 µg

sc-223919A
500 µg
$352.00