Molecular structure of D-chiro Inositol, CAS Number: 643-12-9
D-chiro Inositol (CAS 643-12-9)
See product citations (2)
Alternate Names:
1D-chiro-Inositol; (+)-Inositol; 1,2,4/3,5,6-Hexahydroxycyclohexane
Application:
D-chiro Inositol is an important secondary messenger in insulin signal transduction
CAS Number:
643-12-9
Molecular Weight:
180.16
Molecular Formula:
C6H12O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
D-chiro Inositol is a member of the inositol family of compounds that has interest from various fields of biological research. In studies of cellular signaling, D-chiro Inositol is recognized for its role in insulin signal transduction and its influence on glucose metabolism, which is critical for understanding energy regulation in cells. Biochemists investigate its participation in the phosphoinositide pathway, a complex network of reactions involved in cell membrane dynamics and secondary messaging systems. In plant biology, it is studied for its contribution to osmoregulation and as a component of phytic acid, which plays a role in mineral storage.
D-chiro Inositol (CAS 643-12-9) References
- D-chiro-inositol--its functional role in insulin action and its deficit in insulin resistance. | Larner, J. 2002. Int J Exp Diabetes Res. 3: 47-60. PMID: 11900279
- Potential role and therapeutic interests of myo-inositol in metabolic diseases. | Croze, ML. and Soulage, CO. 2013. Biochimie. 95: 1811-27. PMID: 23764390
- Effects of Inositol(s) in Women with PCOS: A Systematic Review of Randomized Controlled Trials. | Unfer, V., et al. 2016. Int J Endocrinol. 2016: 1849162. PMID: 27843451
- Combining treatment with myo-inositol and D-chiro-inositol (40:1) is effective in restoring ovary function and metabolic balance in PCOS patients. | Monastra, G., et al. 2017. Gynecol Endocrinol. 33: 1-9. PMID: 27898267
- Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility. | Morley, LC., et al. 2017. Cochrane Database Syst Rev. 11: CD003053. PMID: 29183107
- Inositols in Polycystic Ovary Syndrome: An Overview on the Advances. | Facchinetti, F., et al. 2020. Trends Endocrinol Metab. 31: 435-447. PMID: 32396844
- New clinical targets of d-chiro-inositol: rationale and potential applications. | Laganà, AS., et al. 2020. Expert Opin Drug Metab Toxicol. 16: 703-710. PMID: 32552009
- From Myo-inositol to D-chiro-inositol molecular pathways. | Kiani, AK., et al. 2021. Eur Rev Med Pharmacol Sci. 25: 2390-2402. PMID: 33755975
- D-Chiro-Inositol Regulates Insulin Signaling in Human Adipocytes. | Montt-Guevara, MM., et al. 2021. Front Endocrinol (Lausanne). 12: 660815. PMID: 33859622
- Inositols: From Established Knowledge to Novel Approaches. | Dinicola, S., et al. 2021. Int J Mol Sci. 22: PMID: 34638926
- New Insights into the Activities of D-Chiro-Inositol: A Narrative Review. | Gambioli, R., et al. 2021. Biomedicines. 9: PMID: 34680494
- Strategy to improve the female fertility in the general gynecologist's office: use of a nutritional supplement based on myo-inositol/D-chiro-inositol and antioxidants. | Mendoza, N., et al. 2022. Gynecol Endocrinol. 38: 275-278. PMID: 34931570
- D-Chiro-inositol and PCOS: between myth and reality. The never-ending story. | Cianci, A. and Vitale, SG. 2022. Int J Food Sci Nutr. 73: 565-570. PMID: 35057707
- D-Chiro-inositol in PCOS: the myths and what we know about the reality. | Unfer, V. 2022. Int J Food Sci Nutr. 73: 989-991. PMID: 35713196
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D-chiro Inositol, 100 mg | sc-221469A | 100 mg | $143.00 | |||
D-chiro Inositol, 1 g | sc-221469 | 1 g | $265.00 | |||
D-chiro Inositol, 2 g | sc-221469B | 2 g | $398.00 | |||
D-chiro Inositol, 5 g | sc-221469C | 5 g | $561.00 |