Date published: 2026-4-28

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Cyanuric chloride (CAS 108-77-0)

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Alternate Names:
2,4,6-Trichloro-1,3,5-triazine
CAS Number:
108-77-0
Purity:
≥98%
Molecular Weight:
184.41
Molecular Formula:
C3Cl3N3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cyanuric chloride is a chemical compound employed as a versatile reagent in organic synthesis, particularly in the production of dyes, herbicides, and other bioactive compounds. Its reactivity with various nucleophiles, such as amines and alcohols, makes it a valuable compound for introducing –NH- or –OH functional groups into molecules through a chlorination reaction. In polymer chemistry, Cyanuric chloride is studied for its role in cross-linking polymers to enhance their thermal stability and resistance to chemicals. It is also used in the synthesis of coupling agents, which are compounds that improve the adhesion between different materials, such as fibers and resins in composite materials. Furthermore, due to its trifunctional structure, researchers investigate Cyanuric chloride′s utility in creating triazine-based frameworks, which have applications in materials science for the development of novel materials with specific porosity and adsorption characteristics.


Cyanuric chloride (CAS 108-77-0) References

  1. Cyanuric chloride as a mild and active Beckmann rearrangement catalyst.  |  Furuya, Y., et al. 2005. J Am Chem Soc. 127: 11240-1. PMID: 16089442
  2. 2,4-Dichloro-6-[2-meth-oxy-4-(prop-2-en-1-yl)phen-oxy]-1,3,5-triazine.  |  Ma, YT., et al. 2010. Acta Crystallogr Sect E Struct Rep Online. 66: o2946. PMID: 21589116
  3. 1,5-Dichloro-3(2,7),7(2,7)-dinaphthal-ena-2,4,6,8-tetra-oxa-1(2,6),5(2,6)-di(1,3,5-triazina)octa-phane.  |  Sang, QG. and Yang, JK. 2011. Acta Crystallogr Sect E Struct Rep Online. 67: o2525. PMID: 22065129
  4. Cyanuric chloride catalyzed mild protocol for synthesis of biologically active dihydro/spiro quinazolinones and quinazolinone-glycoconjugates.  |  Sharma, M., et al. 2012. J Org Chem. 77: 929-37. PMID: 22181712
  5. Mild and efficient cyanuric chloride catalyzed Pictet-Spengler reaction.  |  Sharma, A., et al. 2013. Beilstein J Org Chem. 9: 1235-42. PMID: 23843919
  6. Cyanuric chloride/sodium borohydride: a new reagent combination for reductive opening of 4,6-benzylidene acetals of carbohydrates to primary alcohols.  |  Tatina, M., et al. 2013. Carbohydr Res. 381: 142-5. PMID: 24103734
  7. Cyanuric chloride as an efficient catalyst for the synthesis of 2,3-unsaturated O-glycosides by Ferrier rearrangement.  |  Yang, X. and Li, N. 2014. ScientificWorldJournal. 2014: 307895. PMID: 24574881
  8. Amino acids as chiral auxiliaries in cyanuric chloride-based chiral derivatizing agents for enantioseparation by liquid chromatography.  |  Batra, S. and Bhushan, R. 2014. Biomed Chromatogr. 28: 1532-46. PMID: 25137358
  9. Infrared Spectroscopic Study of the Adsorption Forms of Cyanuric Acid and Cyanuric Chloride on TiO2.  |  Chien, TE., et al. 2016. Langmuir. 32: 5306-13. PMID: 27176610
  10. A sensitive colorimetric determination of cyanuric chloride and its activated agarose immobilization resins.  |  Miron, T. and Wilchek, M. 2017. Anal Biochem. 527: 1-3. PMID: 28377032
  11. Effect of Occupational Exposure to Cyanuric Chloride on Respiratory Morbidity: Cross-Sectional Analyses of Respiratory Symptoms and Longitudinal Analyses of Lung Function Parameters.  |  Morfeld, P. and Yong, M. 2019. J Occup Environ Med. 61: e1-e11. PMID: 30395008
  12. α-Amylase immobilization on amidoximated acrylic microfibres activated by cyanuric chloride.  |  Almulaiky, YQ., et al. 2018. R Soc Open Sci. 5: 172164. PMID: 30564380
  13. Cyanuric chloride-imidazole dendrimer functionalized nanoparticles as an adsorbent for magnetic solid phase extraction of quaternary ammonium compounds from fruit and vegetable puree based infant foods.  |  Zhao, T., et al. 2021. J Chromatogr A. 1636: 461735. PMID: 33316560
  14. Imine bond transformation of a dynamic Sm(III) macrocycle-based chemosensor: The indirect approach for detecting cyanuric chloride.  |  Zhang, K., et al. 2021. Anal Chim Acta. 1144: 34-42. PMID: 33453795
  15. Cyanuric chloride as the basis for compositionally diverse lipids.  |  Nardo, D., et al. 2021. RSC Adv. 11: 24752-24761. PMID: 34354826

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cyanuric chloride, 250 g

sc-239597
250 g
$43.00

Cyanuric chloride, 1 kg

sc-239597A
1 kg
$148.00