Date published: 2025-10-10

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Cocamidopropyl betaine (CAS 86438-79-1)

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Alternate Names:
{[3-(Dodecanoylamino)propyl](dimethyl)ammonio}acetate
Application:
Cocamidopropyl betaine is a medium strength surfactant
CAS Number:
86438-79-1
Molecular Weight:
342.52
Molecular Formula:
C19H38N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cocamidopropyl betaine is a zwitterion, consisting of both a quaternary ammonium cation and a carboxylate. Cocamidopropyl betaine is used as a medium strength surfactant. Cocamidopropyl betaine, found in coconut oil, is an amphoteric surfactant widely utilized in an array of products spanning shampoos, body washes, cosmetics, and household cleaners. Functioning as a gentle surfactant, it effectively reduces surface tension and generates a foaming action when combined with water. Furthermore, it exhibits remarkable abilities in stabilizing and emulsifying other ingredients within various formulations. Beyond its practical applications, cocamidopropyl betaine plays a significant role in scientific research. It has been employed to investigate the impact of surfactants on the environment and has contributed to the development of novel surfactants.


Cocamidopropyl betaine (CAS 86438-79-1) References

  1. Toxicity of the amphoteric surfactant, cocamidopropyl betaine, to the marine macroalga, Ulva lactuca.  |  Vonlanthen, S., et al. 2011. Ecotoxicology. 20: 202-7. PMID: 21082243
  2. Occupational contact allergy to cocamidopropyl betaine and its impurities.  |  Suuronen, K., et al. 2012. Contact Dermatitis. 66: 286-92. PMID: 22364510
  3. Final report of the Cosmetic Ingredient Review Expert Panel on the safety assessment of cocamidopropyl betaine (CAPB).  |  Burnett, CL., et al. 2012. Int J Toxicol. 31: 77S-111S. PMID: 22869896
  4. Cutaneous Delayed-Type Hypersensitivity to Surfactants.  |  Fowler, JF., et al. 2015. Dermatitis. 26: 268-70. PMID: 26551605
  5. From well-entangled to partially-entangled wormlike micelles.  |  Zou, W., et al. 2019. Soft Matter. 15: 642-655. PMID: 30608505
  6. Allergens in Medical Hand Skin Cleansers.  |  Rodriguez-Homs, LG. and Atwater, AR. 2019. Dermatitis. 30: 336-341. PMID: 31724988
  7. Effect of plasticizer and surfactant on the properties of poly(vinyl alcohol)/chitosan films.  |  Stachowiak, N., et al. 2020. Int J Biol Macromol. 164: 2100-2107. PMID: 32758608
  8. In Situ Nanostructural Analysis of Concentrated Wormlike Micellar Fluids Comprising Sodium Laureth Sulfate and Cocamidopropyl Betaine Using Small-Angle Neutron Scattering.  |  Williams, AP., et al. 2020. Langmuir. 36: 14296-14305. PMID: 33202134
  9. Effects of a Multicomponent Perfume Accord and Dilution on the Formation of ST2S/CAPB Mixed-Surfactant Microemulsions.  |  Mirzamani, M., et al. 2022. Langmuir. 38: 1334-1347. PMID: 35051338
  10. Morphology-controlled silver nanowire synthesis using a cocamidopropyl betaine-based polyol process for flexible and stretchable electronics.  |  Li, Y., et al. 2020. RSC Adv. 10: 21369-21374. PMID: 35518736
  11. Micellar and sub-micellar chromatography with a cocamidopropyl betaine surfactant.  |  Wilson, KM. and Danielson, ND. 2022. J Chromatogr A. 1681: 463442. PMID: 36058078
  12. Effect of New Surfactants on Biological Properties of Liquid Soaps.  |  Klimaszewska, E., et al. 2022. Molecules. 27: PMID: 36080193
  13. Transcriptomic analysis provides insights into the algicidal mechanism of cocamidopropyl betaine against the red tide microalgae Skeletonema costatum.  |  Zhang, B., et al. 2023. Mar Environ Res. 183: 105838. PMID: 36525828
  14. Synthesis and characterization of selenium nanoparticles stabilized with cocamidopropyl betaine.  |  Blinov, AV., et al. 2022. Sci Rep. 12: 21975. PMID: 36539549
  15. Optimization of the Technique for Obtaining Selenium Nanoparticles Stabilized with Cocamidopropyl Betaine.  |  Blinov, AV., et al. 2022. Russ J Gen Chem. 92: 2939-2943. PMID: 36778663

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cocamidopropyl betaine, 5 g

sc-357318
5 g
$162.00

Cocamidopropyl betaine, 25 g

sc-357318A
25 g
$413.00