Clindamycin is an antibiotic which inhibits bacterial protein synthesis and is concentration dependent. Sensitive organisms to Clindamycin are usually gram-positive cocci and many anaerobic bacteria. As an inhibitor of protein synthesis, Clindamycin binds to the 50s ribosomal subunit and is reported to inhibit peptidyltransferase and therfore affecting the process of peptide chain initiation. Additionally reported to possibly stimulate the dissociation of peptidyl-tRNA from ribosomes, therefore inhibiting protein synthesis.
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