Date published: 2025-9-25

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cis-Diamminedinitratoplatinum (CAS 41575-87-5)

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Alternate Names:
(SP-4-2)-Diamminebis(nitrato-?O)platinum; cis-Diamminebis(nitrito-O)platinum
Application:
cis-Diamminedinitratoplatinum is potential anticancer agent for brain tumors
CAS Number:
41575-87-5
Molecular Weight:
353.15
Molecular Formula:
H6N4O6Pt
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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cis-Diamminedinitratoplatinum is a platinum coordination complex that has attention in the field of inorganic chemistry and is frequently employed in research that investigates the interactions of metal complexes with biomolecules. Its structure, consisting of a platinum center with ammine ligands and nitrate groups in a cis configuration, allows scientists to study its binding affinity and reaction mechanisms with nucleic acids and proteins. This compound is particularly useful for understanding DNA-protein interactions, DNA repair mechanisms, and the structural perturbations metal complexes can induce in biological macromolecules. In addition, cis-Diamminedinitratoplatinum is used as a reference or starting material in the synthesis of novel platinum-based compounds, which may have unique physical or chemical properties for potential applications in catalysis or materials science.


cis-Diamminedinitratoplatinum (CAS 41575-87-5) References

  1. Novel and simple loading procedure of cisplatin into liposomes and targeting tumor endothelial cells.  |  Hirai, M., et al. 2010. Int J Pharm. 391: 274-83. PMID: 20211714
  2. Octreotide labeled aggregates containing platinum complexes as nanovectors for drug delivery.  |  Accardo, A., et al. 2013. J Pept Sci. 19: 190-7. PMID: 23355401
  3. Second- and higher-order structural changes of DNA induced by antitumor-active tetrazolato-bridged dinuclear platinum(II) complexes with different types of 5-substituent.  |  Uemura, M., et al. 2013. J Inorg Biochem. 127: 169-74. PMID: 23725767
  4. VEGF- and VEGFR2-Targeted Liposomes for Cisplatin Delivery to Glioma Cells.  |  Shein, SA., et al. 2016. Mol Pharm. 13: 3712-3723. PMID: 27654150
  5. Cisplatin-loaded, Sialyl Lewis X-Modified Liposomes: Drug Release, Biodistribution and Antitumor Efficacy.  |  Kishimoto, S., et al. 2017. Anticancer Res. 37: 6055-6061. PMID: 29061785

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

cis-Diamminedinitratoplatinum, 5 mg

sc-391730
5 mg
$350.00

cis-Diamminedinitratoplatinum, 10 mg

sc-391730A
10 mg
$615.00

cis-Diamminedinitratoplatinum, 25 mg

sc-391730B
25 mg
$1390.00