CIB2 Antibody (CIB2C12B11): sc-81068
- CIB2 Antibody (CIB2C12B11) is a mouse monoclonal IgG1 CIB2 antibody provided at 100 µg/ml
- raised against a recombinant protein corresponding to the C-terminal region of CIB2 of human origin
- recommended for detection of CIB2 of mouse, rat and human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CIB2 Antibody (CIB2C12B11). This work is in progress.
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CIB2 Antibody (CIB2C12B11) is a mouse monoclonal IgG1 antibody that detects CIB2 protein of mouse, rat, and human origin by western blotting (WB) and immunoprecipitation (IP). Anti-CIB2 antibody (CIB2C12B11) is available as a non-conjugated format. CIB2, or Calcium and integrin-binding family member 2, is a 187 amino acid protein encoded by the human gene CIB2 and is characterized by three EF-hand domains, which are critical for calcium binding. CIB2 plays a significant role in various cellular signaling pathways, particularly in muscle tissue, where CIB2 interacts with integrins and calcium to mediate cellular responses. CIB2 is closely related to CIB1, which is known for its role in platelet function and signal transduction. CIB2 expression is significantly reduced in conditions such as Laminin α-2 chain deficiency, suggesting involvement in the pathogenesis of congenital muscular dystrophies like MDC1A. CIB2′s ability to bind to Integrin α7 and calcium highlights a multifaceted role in muscle signaling and development, making CIB2 an important target for research into muscle-related diseases and signaling mechanisms.
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CIB2 Antibody (CIB2C12B11) References:
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CIB2 Antibody (CIB2C12B11) | sc-81068 | 100 µg/ml | $333.00 |