Date published: 2026-5-21

1-800-457-3801

SCBT Portrait Logo
Seach Input

Chloroacetaldehyde diethyl acetal (CAS 621-62-5)

0.0(0)
Write a reviewAsk a question

Alternate Names:
2-Chloro-1,1-diethoxyethane, Chloroacetal
CAS Number:
621-62-5
Molecular Weight:
152.62
Molecular Formula:
C6H13ClO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Chloroacetaldehyde diethyl acetal is an organic compound that exists as a colorless liquid with a distinct odor. This versatile compound serves as a valuable reagent in organic synthesis and acts as a fundamental building block for synthesizing various compounds. In scientific research, Chloroacetaldehyde diethyl acetal finds extensive use across diverse applications. It serves as a protecting group in peptide synthesis and operates as a reagent in organic synthesis. Furthermore, it plays a vital role in the preparation of oxazolidinones and imidazolidinones. Although the precise mechanism of action of Chloroacetaldehyde diethyl acetal is not fully elucidated, it is believed that the reaction between an aldehyde or ketone with ethyl chloroformate results in the formation of chloroacetal through a nucleophilic substitution reaction. Similarly, the reaction of an aldehyde or ketone with chloroacetyl chloride or bromide is thought to proceed via a nucleophilic addition reaction.


Chloroacetaldehyde diethyl acetal (CAS 621-62-5) References

  1. Membrane-permeable luciferin esters for assay of firefly luciferase in live intact cells.  |  Craig, FF., et al. 1991. Biochem J. 276 (Pt 3): 637-41. PMID: 2064603
  2. Reversible Self-Assembly Nanovesicle of UCST Response Prepared with Multi-l-arginyl-poly-l-aspartate Conjugated with Polyethylene Glycol.  |  Tseng, WC., et al. 2018. Biomacromolecules. 19: 4585-4592. PMID: 30395453
  3. Efficient Synthesis of α-Branched Purine-Based Acyclic Nucleosides: Scopes and Limitations of the Method.  |  Frydrych, J., et al. 2020. Molecules. 25: PMID: 32961820
  4. Investigations on metabolism and carcinogenicity of 1,1,2-trichloroethane.  |  Norpoth, K., et al. 1988. J Cancer Res Clin Oncol. 114: 158-62. PMID: 3350848
  5. Synthesis of camalexin and related phytoalexins  |  WA Ayer, PA Craw, Y Ma, S Miao - Tetrahedron, 1992 - Elsevier. 1992,. Tetrahedron. Volume 48, Issue 14,: Pages 2919-2924.
  6. A HIGH YIELDING, REPRODUCIBLE SYNTHESIS OF TRIMETHYLSILYLKETENE  |  T. Howard Black, et al. 2002 -. Synthetic Communications An International Journal for Rapid Communication of Synthetic Organic Chemistry. Volume 32, Issue 13: Pages 2083-2088.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Chloroacetaldehyde diethyl acetal, 100 g

sc-239511
100 g
$204.00