Molecular structure of Chloro-APB hydrobromide, CAS Number: 80751-65-1
Chloro-APB hydrobromide (CAS 80751-65-1)
Alternate Names:
6-Chloro-N-allyl-SKF-38393 hydrobromide; (±)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
Application:
Chloro-APB hydrobromide is a full D1 dopamine receptor agonist
CAS Number:
80751-65-1
Molecular Weight:
410.73
Molecular Formula:
C19H20ClNO2•HBr
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Full D1 dopamine receptor agonist.
Chloro-APB hydrobromide (CAS 80751-65-1) References
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- Transgenic mice expressing a truncated form of CREB-binding protein (CBP) exhibit deficits in hippocampal synaptic plasticity and memory storage. | Wood, MA., et al. 2005. Learn Mem. 12: 111-9. PMID: 15805310
- Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning. | Kellendonk, C., et al. 2006. Neuron. 49: 603-15. PMID: 16476668
- Behavioral and molecular effects of dopamine D1 receptor stimulation during naloxone-precipitated morphine withdrawal. | Chartoff, EH., et al. 2006. J Neurosci. 26: 6450-7. PMID: 16775132
- Oxidant-induced cardiomyocyte injury: identification of the cytoprotective effect of a dopamine 1 receptor agonist using a cell-based high-throughput assay. | Gerö, D., et al. 2007. Int J Mol Med. 20: 749-61. PMID: 17912470
- Anatomically dissociable effects of dopamine D1 receptor agonists on reward and relief of withdrawal in morphine-dependent rats. | Chartoff, EH., et al. 2009. Psychopharmacology (Berl). 204: 227-39. PMID: 19148621
- Dopaminergic modulation of afferent synaptic transmission in the semicircular canals of frogs. | Andrianov, GN., et al. 2009. Neurosignals. 17: 222-8. PMID: 19546593
- Effect of GDNF on depressive-like behavior, spatial learning and key genes of the brain dopamine system in genetically predisposed to behavioral disorders mouse strains. | Naumenko, VS., et al. 2014. Behav Brain Res. 274: 1-9. PMID: 25101543
- The dopamine D1 receptor agonist SKF-82958 effectively increases eye blinking count in common marmosets. | Kotani, M., et al. 2016. Behav Brain Res. 300: 25-30. PMID: 26675887
- Dopamine D1 receptor in the NAc shell is involved in delayed emergence from isoflurane anesthesia in aged mice. | Zhang, Y., et al. 2021. Brain Behav. 11: e01913. PMID: 33094567
- Dopamine D1 Receptor in the Nucleus Accumbens Modulates the Emergence from Propofol Anesthesia in Rat. | Zhang, Y., et al. 2021. Neurochem Res. 46: 1435-1446. PMID: 33683630
- Differential inhibition of secretagogue-stimulated sodium uptake in adrenal chromaffin cells by activation of D4 and D5 dopamine receptors. | Dahmer, MK. and Senogles, SE. 1996. J Neurochem. 67: 1960-4. PMID: 8863501
Activator of:
D1DR, and DOR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Chloro-APB hydrobromide, 5 mg | sc-252573 | 5 mg | $154.00 | |||
Chloro-APB hydrobromide, 25 mg | sc-252573A | 25 mg | $527.00 |