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Prostacyclin (PGI2) is a cyclooxygenase metabolite with antithrombotic properties found in vascular endothelial cells. The half-life is short both in vivo and in vitro, ranging from 30 seconds to a few minutes. CG 4305 is a stable carbacyclic analog of PGI2 that inhibits ADP-induced platelet aggregation 25% at a concentration of 50 nM. Doses of 10 mg/kg (oral) or 1 mg/kg (intraduodenal) have been shown to prevent rabbit carotid artery thrombosis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CG 4305, 100 µg | sc-300343 | 100 µg | $107.00 | |||
CG 4305, 500 µg | sc-300343A | 500 µg | $480.00 |