Date published: 2025-12-1

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Cevimeline N-Oxide (CAS 469890-14-0)

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Alternate Names:
(2′R,3R)-rel-2′-Methylspiro[1-azabicyclo[2.2.2]octane-3,5′-oxathiolane] 1-Oxide
CAS Number:
469890-14-0
Molecular Weight:
215.31
Molecular Formula:
C10H17NO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cevimeline N-Oxide functions as a potent and selective agonist for muscarinic acetylcholine receptors. It acts by binding to and activating these receptors, leading to the stimulation of phospholipase C and the subsequent release of intracellular calcium ions. This activation of muscarinic receptors results in the modulation of various cellular processes, including the regulation of neurotransmitter release, smooth muscle contraction, and glandular secretion. At the molecular level, Cevimeline N-Oxide interacts with the binding site of muscarinic receptors, inducing conformational changes that initiate downstream signaling cascades. Through its mechanism of action, Cevimeline N-Oxide can be utilized to investigate the physiological and pharmacological roles of muscarinic receptors in cellular and tissue-based experimental models.


Cevimeline N-Oxide (CAS 469890-14-0) References

  1. Neuropharmacology of Cevimeline and Muscarinic Drugs-Focus on Cognition and Neurodegeneration.  |  Oleksak, P., et al. 2021. Int J Mol Sci. 22: PMID: 34445613

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cevimeline N-Oxide, 1 mg

sc-211060
1 mg
$380.00