Molecular structure of Ceftazidime, CAS Number: 72558-82-8
Ceftazidime (CAS 72558-82-8)
See product citations (3)
Alternate Names:
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Application:
Ceftazidime is an antimicrobial small molecule
CAS Number:
72558-82-8
Purity:
≥99%
Molecular Weight:
546.58
Molecular Formula:
C22H22N6O7S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ceftazidime impedes bacterial growth by binding to the IL-2 receptor, an enzyme for protein synthesis. Ceftazidime has demonstrated effectiveness against both Gram-negative and Gram-positive bacteria in in vitro studies. It exhibits activity against relevant Gram-negative bacteria including Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis, and Gram-positive bacteria Staphylococcus aureus and Streptococcus pneumoniae. In the realm of environmental science, ceftazidime can be used as a reference material for the development of analytical methods aimed at detecting and quantifying similar compounds in environmental samples. This is important for monitoring pollutants and understanding their distribution, degradation, and impact on ecosystems.
Ceftazidime (CAS 72558-82-8) References
- Efficacy of ceftazidime/avibactam in monotherapy or combination therapy against carbapenem-resistant Gram-negative bacteria: A meta-analysis. | Onorato, L., et al. 2019. Int J Antimicrob Agents. 54: 735-740. PMID: 31479738
- Pharmacoepidemiology of Ceftazidime-Avibactam Use: A Retrospective Cohort Analysis of 210 US Hospitals. | Strich, JR., et al. 2021. Clin Infect Dis. 72: 611-621. PMID: 32107536
- Ceftazidime-Avibactam Resistance Mediated by the N346Y Substitution in Various AmpC β-Lactamases. | Compain, F., et al. 2020. Antimicrob Agents Chemother. 64: PMID: 32253219
- Ceftazidime/avibactam in the era of carbapenemase-producing Klebsiella pneumoniae: experience from a national registry study. | Karaiskos, I., et al. 2021. J Antimicrob Chemother. 76: 775-783. PMID: 33249436
- Ceftazidime induced liver injury. | Shah, T., et al. 2021. BMJ Case Rep. 14: PMID: 34887294
- Selection of AmpC β-Lactamase Variants and Metallo-β-Lactamases Leading to Ceftolozane/Tazobactam and Ceftazidime/Avibactam Resistance during Treatment of MDR/XDR Pseudomonas aeruginosa Infections. | Ruedas-López, A., et al. 2022. Antimicrob Agents Chemother. 66: e0206721. PMID: 34930034
- Co-resistance to ceftazidime-avibactam and cefiderocol in clinical isolates producing KPC variants. | Poirel, L., et al. 2022. Eur J Clin Microbiol Infect Dis. 41: 677-680. PMID: 35088164
- Rapid Decline of Ceftazidime Resistance in Antibiotic-Free and Sublethal Environments Is Contingent on Genetic Background. | Hernando-Amado, S., et al. 2022. Mol Biol Evol. 39: PMID: 35291010
- Evaluation of Ceftazidime Use in the Neonatal Intensive Care Unit and Association With Cephalosporin-Resistant Gram-Negative Bacteria. | Mayes, RA., et al. 2022. Ann Pharmacother. 56: 1325-1332. PMID: 35484966
- Ceftazidime pharmacokinetics in dogs after intravenous injection and delivered with the RxActuator Mini-Infuser infusion pump. | Papich, MG., et al. 2022. J Vet Emerg Crit Care (San Antonio). 32: 608-615. PMID: 35522422
- Comparison of ceftazidime-avibactam susceptibility testing methods against OXA-48-like carrying Klebsiella blood stream isolates. | Isler, B., et al. 2022. Diagn Microbiol Infect Dis. 104: 115745. PMID: 35843111
- Ceftazidime-Avibactam plus Aztreonam for the Treatment of Infections by VIM-Type-Producing Gram-Negative Bacteria. | Sempere, A., et al. 2022. Antimicrob Agents Chemother. 66: e0075122. PMID: 36102635
- Ceftazidime-avibactam activity against Gram-negative respiratory isolates collected between 2018 and 2019. | Kempf, M., et al. 2022. J Glob Antimicrob Resist. 31: 239-247. PMID: 36208850
- Complex-Forming Properties of Ceftazidime with Fe(III) Ions in an Aqueous Solution. | Pająk, M., et al. 2022. Molecules. 27: PMID: 36364052
- Investigation of ceftazidime-avibactam susceptibility in clinical isolates of gram-negative bacteria. | Dumlu, R., et al. 2022. Turk J Med Sci. 52: 1839-1844. PMID: 36945980
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ceftazidime, 1 g | sc-205243 | 1 g | $132.00 | |||
Ceftazidime, 5 g | sc-205243A | 5 g | $520.00 |