


CD109 Antibody (B-9) is a mouse monoclonal IgG2a antibody that detects CD109 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CD109 is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a crucial role in various biological processes, particularly in the context of cancer. CD109 is a member of the α-Macroglobulin/C3, C4, C5 family of thioester-containing proteins and is notably expressed in CD34+ acute myeloid leukemia cell lines, activated T lymphoblasts, activated platelets, endothelial cells, and certain carcinomas, including lung and esophageal squamous cell types. CD109 exhibits characteristics of a cancer-testis antigen, which can be pivotal in cancer immunotherapy. Additionally, CD109 carries the platelet-specific Gov antigen system, which is essential for understanding complications related to platelet transfusions, such as transfusion refractoriness and neonatal alloimmune thrombocytopenia. Anti-CD109 antibody (B-9) effectively targets CD109, making this antibody a valuable tool for researchers investigating CD109′s role in hematological malignancies and other related conditions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD109 Antibody (B-9) | sc-271039 | 200 µg/ml | $322.00 | |||
CD109 Antibody (B-9): m-IgG Fc BP-HRP Bundle | sc-540196 | 200 µg Ab; 10 µg BP | $361.00 |