Cardiotrophin-1 Antibody (4916): sc-73763
- Cardiotrophin-1 Antibody (4916) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against full length recombinant Cardiotrophin-1 of human origin
- recommended for detection of Cardiotrophin-1 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Cardiotrophin-1 Antibody (4916). This work is in progress.
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Cardiotrophin-1 Antibody (4916) is a mouse monoclonal IgG1 antibody that detects Cardiotrophin-1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Cardiotrophin-1 is a crucial member of the IL-6 family of cytokines, known for its role in cardiac development and function. This secreted protein is predominantly expressed in the myocardium during cardiogenesis, where Cardiotrophin-1 plays a vital role in promoting the proliferation and survival of embryonic cardiomyocytes. By binding to the leukemia inhibitory factor receptor/gp130 receptor complex, Cardiotrophin-1 activates signaling pathways that lead to cardiac myocyte hypertrophy, which is essential for heart adaptation to stress and injury. Cardiotrophin-1 expression is notably high in the heart, prostate, ovary, and skeletal muscle, while lower levels are found in the lung, kidney, pancreas, thymus, testis, and small intestine. Understanding Cardiotrophin-1 function is important not only for insights into cardiac development but also for potential therapeutic applications in heart diseases, making anti-Cardiotrophin-1 antibody (4916) an invaluable tool for researchers studying cardiovascular biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cardiotrophin-1 Antibody (4916) | sc-73763 | 100 µg/ml | $322.00 |