CaMKKβ Antibody (239CT7.5.3): sc-517319
- CaMKKβ Antibody (239CT7.5.3) is a mouse monoclonal IgM provided at 100 µg/ml
- raised against a recombinant protein corresponding to CaMKKβ of human origin
- recommended for detection of CaMKKβ of mouse, rat and human origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CaMKKβ Antibody (239CT7.5.3). This work is in progress.
CaMKKβ Antibody (239CT7.5.3) is a mouse monoclonal IgM antibody that detects CaMKKβ in mouse, rat, and human samples through western blotting (WB). CaMKKβ, or calcium/calmodulin-dependent protein kinase kinase beta, plays a crucial role in cellular signaling pathways by acting as a key regulator of CaMKI and CaMKIV activation through phosphorylation. CaMKKβ is primarily located in the cytoplasm, where CaMKKβ is essential for mediating calcium signaling and facilitating various physiological processes, including muscle contraction, neurotransmitter release, and gene expression. CaMKKβ′s cytoplasmic localization enables rapid responses to changes in intracellular calcium levels, thereby influencing downstream signaling cascades that maintain cellular homeostasis and respond to external stimuli. Anti-CaMKKβ antibody (239CT7.5.3) helps researchers effectively study calcium signaling dynamics and implications in various biological contexts, including neurobiology and cardiovascular health.
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CaMKKβ Antibody (239CT7.5.3) References:
- Clopidogrel Protects Endothelium by Hindering TNFα-Induced VCAM-1 Expression through CaMKKβ/AMPK/Nrf2 Pathway. | Yang, H., et al. 2016. J Diabetes Res. 2016: 9128050. PMID: 26824050
- TRPC5-induced autophagy promotes drug resistance in breast carcinoma via CaMKKβ/AMPKα/mTOR pathway. | Zhang, P., et al. 2017. Sci Rep. 7: 3158. PMID: 28600513
- Activation of CaMKKβ/AMPKα pathway by 2-AG in human platelets. | Signorello, MG. and Leoncini, G. 2018. J Cell Biochem. 119: 876-884. PMID: 28661046
- Saxagliptin regulates M1/M2 macrophage polarization via CaMKKβ/AMPK pathway to attenuate NAFLD. | Yang, Y., et al. 2018. Biochem Biophys Res Commun. 503: 1618-1624. PMID: 30060948
- Propofol inhibited autophagy through Ca2+/CaMKKβ/AMPK/mTOR pathway in OGD/R-induced neuron injury. | Sun, B., et al. 2018. Mol Med. 24: 58. PMID: 30470173
- DJ-1 regulates tyrosine hydroxylase expression through CaMKKβ/CaMKIV/CREB1 pathway in vitro and in vivo. | Xu, X., et al. 2020. J Cell Physiol. 235: 869-879. PMID: 31232473
- Ca2+ Regulates Autophagy Through CaMKKβ/AMPK/mTOR Signaling Pathway in Mechanical Spinal cord Injury: An in vitro Study. | Liu, FS., et al. 2023. Neurochem Res. 48: 447-457. PMID: 36315370
- Microcystin leucine arginine induces human sperm damage: Involvement of the Ca2+/CaMKKβ/AMPK pathway. | Guo, X., et al. 2023. Ecotoxicol Environ Saf. 256: 114845. PMID: 37001189
- JS-K activates G2/M checkpoints through the DNA damage response and induces autophagy via CAMKKβ/AMPKα/mTOR pathway in bladder cancer cells. | Zhao, Y., et al. 2024. J Cancer. 15: 343-355. PMID: 38169515
- Aβ25-35-induced autophagy and apoptosis are prevented by the CRMP2-derived peptide ST2-104 (R9-CBD3) via a CaMKKβ/AMPK/mTOR signaling hub. | Ji, Y., et al. 2024. PLoS One. 19: e0309794. PMID: 39325788
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CaMKKβ Antibody (239CT7.5.3) | sc-517319 | 100 µg/ml | $322.00 |