c-Fms/CSF-1R Antibody (2-4A5): sc-01
- c-Fms/CSF-1R Antibody (2-4A5) is a rat monoclonal IgG1, cited in 12 publications, provided at 200 µg/ml
- raised against the cell surface (extracellular) epitope of c-Fms/CSF-1R of human origin
- c-Fms/CSF-1R Antibody (2-4A5) is recommended for detection of c-Fms gp130 and gp150 of human origin by WB and IP
- Anti-c-Fms/CSF-1R Antibody (2-4A5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of c-Fms/CSF-1R (2-4A5): sc-01.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for c-Fms/CSF-1R Antibody (2-4A5). This work is in progress.
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SEE ALSO...
c-Fms/CSF-1R Antibody (2-4A5) is an IgG1 rat monoclonal c-Fms/CSF-1R antibody (also designated c-Fms/CSF-1R antibody or antibody) that detects c-Fms gp130 and gp150 of human origin. c-Fms/CSF-1R Antibody (2-4A5) is available as the non-conjugated anti-c-Fms/CSF-1R antibody form, as well as multiple conjugated forms of anti-c-Fms/CSF-1R antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. c-Fms/CSF-1R, also designated macrophage colony-stimulating factor receptor (M-CSFR), FIM2 or CD115, is a transmembrane tyrosine kinase receptor belonging to the CSF1/PDGF receptor family. It is encoded by the c-Fms proto-oncogene and is expressed in mononuclear phagocytes, oocytes, decidual cells, trophoblastic cells and some myoblasts. It is important for growth and differentiation of myeloid cells and its function can be regulated by SLAP-2. c-Fms/CSF-1R is responsible for mediating all of the functions of M-CSF. M-CSF is a glycoprotein required for the proliferation and differentiation of mononuclear phagocytes, including osteoclasts. M-CSF has also been identified as an important mediator of the inflammatory response and can regulate the release of proinflammatory cytokines from macrophages.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
c-Fms/CSF-1R Antibody (2-4A5) | sc-01 | 200 µg/ml | $316.00 | |||
c-Fms/CSF-1R Antibody (2-4A5) AC | sc-01 AC | 500 µg/ml, 25% agarose | $416.00 | |||
c-Fms/CSF-1R Antibody (2-4A5) HRP | sc-01 HRP | 200 µg/ml | $316.00 | |||
c-Fms/CSF-1R Antibody (2-4A5) FITC | sc-01 FITC | 200 µg/ml | $330.00 | |||
c-Fms/CSF-1R Antibody (2-4A5) PE | sc-01 PE | 200 µg/ml | $343.00 | |||
c-Fms/CSF-1R Antibody (2-4A5) Alexa Fluor® 488 | sc-01 AF488 | 200 µg/ml | $357.00 | |||
c-Fms/CSF-1R Antibody (2-4A5) Alexa Fluor® 546 | sc-01 AF546 | 200 µg/ml | $357.00 | |||
c-Fms/CSF-1R Antibody (2-4A5) Alexa Fluor® 594 | sc-01 AF594 | 200 µg/ml | $357.00 | |||
c-Fms/CSF-1R Antibody (2-4A5) Alexa Fluor® 647 | sc-01 AF647 | 200 µg/ml | $357.00 | |||
c-Fms/CSF-1R Antibody (2-4A5) Alexa Fluor® 680 | sc-01 AF680 | 200 µg/ml | $357.00 | |||
c-Fms/CSF-1R Antibody (2-4A5) Alexa Fluor® 790 | sc-01 AF790 | 200 µg/ml | $357.00 |