C/EBP ε Antibody (C-10): sc-515192
- C/EBP ε Antibody (C-10) is a mouse monoclonal IgG1 κ C/EBP ε antibody, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 1-75 of C/EBP ε of human origin
- C/EBP epsilon Antibody (C-10) is recommended for detection of C/EBP ε of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-C/EBP epsilon Antibody (C-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-515192 X, 200 µg/0.1 ml)
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for C/EBP ε Antibody (C-10). This work is in progress.
C/EBP ε Antibody (C-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects C/EBP epsilon (C/EBP ε) protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-C/EBP ε antibody (C-10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. C/EBP ε (C-10) antibody recognizes a protein that plays a crucial role in regulating gene expression, particularly in immune response and adipogenesis, making C/EBP ε essential for maintaining metabolic homeostasis and proper immune function. Located primarily in the nucleus, C/EBP ε functions as a transcription factor that binds to specific DNA sequences, influencing gene transcription involved in these processes. C/EBP ε forms heterodimers with other C/EBP family members, such as C/EBP α and C/EBP β, enhancing regulatory capacity and allowing coordinated response to various physiological stimuli. C/EBP ε′s significance in cellular differentiation and disease development highlights this protein′s relevance in both basic research and clinical applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
C/EBP ε Antibody (C-10) References:
- C/EBPepsilon directly interacts with the DNA binding domain of c-myb and cooperatively activates transcription of myeloid promoters. | Verbeek, W., et al. 1999. Blood. 93: 3327-37. PMID: 10233885
- Identification of murine and human XCP1 genes as C/EBP-epsilon-dependent members of FIZZ/Resistin gene family. | Chumakov, AM., et al. 2004. Oncogene. 23: 3414-25. PMID: 15064728
- Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. | Cao, Z., et al. 1991. Genes Dev. 5: 1538-52. PMID: 1840554
- A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro. | Williams, SC., et al. 1991. Genes Dev. 5: 1553-67. PMID: 1884998
- CCAAT-enhancer binding protein: a component of a differentiation switch. | Umek, RM., et al. 1991. Science. 251: 288-92. PMID: 1987644
- Cooperative Activity of GABP with PU.1 or C/EBPε Regulates Lamin B Receptor Gene Expression, Implicating Their Roles in Granulocyte Nuclear Maturation. | Malu, K., et al. 2016. J Immunol. 197: 910-22. PMID: 27342846
- Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein. | Birkenmeier, EH., et al. 1989. Genes Dev. 3: 1146-56. PMID: 2792758
- Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses. | Johnson, PF., et al. 1987. Genes Dev. 1: 133-46. PMID: 2824279
- Isolation of a recombinant copy of the gene encoding C/EBP. | Landschulz, WH., et al. 1988. Genes Dev. 2: 786-800. PMID: 2850264
- Loss of myeloid-specific lamin A/C drives lung metastasis through Gfi-1 and C/EBPε-mediated granulocytic differentiation. | Ishii, H., et al. 2020. Mol Carcinog. 59: 679-690. PMID: 31912614
- Cloning of the cDNA encoding human C/EBP gamma, a protein binding to the PRE-I enhancer element of the human interleukin-4 promoter. | Davydov, IV., et al. 1995. Gene. 161: 271-5. PMID: 7665092
- Modulation of mRNA expression of a novel human myeloid-selective CCAAT/enhancer binding protein gene (C/EBP epsilon). | Chih, DY., et al. 1997. Blood. 90: 2987-94. PMID: 9376579
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
C/EBP ε Antibody (C-10) | sc-515192 | 200 µg/ml | $322.00 | |||
C/EBP ε Antibody (C-10) X | sc-515192 X | 200 µg/0.1 ml | $322.00 | |||
C/EBP ε Antibody (C-10) AC | sc-515192 AC | 500 µg/ml, 25% agarose | $424.00 | |||
C/EBP ε Antibody (C-10) HRP | sc-515192 HRP | 200 µg/ml | $322.00 | |||
C/EBP ε Antibody (C-10) FITC | sc-515192 FITC | 200 µg/ml | $336.00 | |||
C/EBP ε Antibody (C-10) PE | sc-515192 PE | 200 µg/ml | $349.00 | |||
C/EBP ε Antibody (C-10) Alexa Fluor® 488 | sc-515192 AF488 | 200 µg/ml | $364.00 | |||
C/EBP ε Antibody (C-10) Alexa Fluor® 546 | sc-515192 AF546 | 200 µg/ml | $364.00 | |||
C/EBP ε Antibody (C-10) Alexa Fluor® 594 | sc-515192 AF594 | 200 µg/ml | $364.00 | |||
C/EBP ε Antibody (C-10) Alexa Fluor® 647 | sc-515192 AF647 | 200 µg/ml | $364.00 | |||
C/EBP ε Antibody (C-10) Alexa Fluor® 680 | sc-515192 AF680 | 200 µg/ml | $364.00 | |||
C/EBP ε Antibody (C-10) Alexa Fluor® 790 | sc-515192 AF790 | 200 µg/ml | $364.00 |