BPV Antibody (5091): sc-58094

BPV Antibody (5091) is a mouse monoclonal IgG1 antibody that detects the BPV protein of non-species reactive by enzyme-linked immunosorbent assay (ELISA). Anti-BPV antibody (5091) is available as the non-conjugated form, specifically designed to facilitate the study of bovine papillomavirus (BPV), which are small, non-enveloped viruses characterized by their icosahedral shape and circular double-stranded DNA genome. The BPV genome is divided into early and late regions, with the early region encoding nonstructural proteins E1 to E8, while the late region encodes structural proteins L1 and L2. Notably, the E2 protein plays a crucial role as the master regulator of papillomavirus transcription and replication, with its activity finely tuned through sequence-specific DNA binding. Understanding the function of the E2 protein is vital, as E2 not only orchestrates viral gene expression but also influences the viral life cycle and pathogenesis, making E2 a key target for therapeutic interventions. BPV is classified into six types, which are further divided into two subgroups, A and B; subgroup B viruses cause warts with a cauliflower-like appearance, predominantly affecting the head, neck, and shoulders in humans, while subgroup A viruses lead to cutaneous fibropapillomas that present as nodular lesions. BPV monoclonal antibody (5091) specificity and sensitivity make this reagent an essential tool for researchers investigating the molecular mechanisms of BPV infection and its associated diseases.

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BPV Antibody (5091) References:

1. Inhibition of the bovine papillomavirus E2 protein activity by peptide nucleic acid.  |  Kurg, R., et al. 2000. Virus Res. 66: 39-50. PMID: 10653916
2. Monitoring and purification of proteins using bovine papillomavirus E2 epitope tags.  |  Kaldalu, N., et al. 2000. Biotechniques. 28: 456-60, 462. PMID: 10723557
3. SOME PROPERTIES OF BOVINE PAPILLOMA VIRUS.  |  BOIRON, M., et al. 1964. Nature. 201: 423-4. PMID: 14110027
4. Association of bovine papillomavirus E2 protein with nuclear structures in vivo.  |  Kurg, R., et al. 2005. J Virol. 79: 10528-39. PMID: 16051845
5. A phosphorylation map of the bovine papillomavirus E1 helicase.  |  Lentz, MR., et al. 2006. Virol J. 3: 13. PMID: 16524476
6. Studies on connective tissue tumors in the hamster produced by bovine papilloma virus.  |  Cheville, NF. 1966. Cancer Res. 26: 2334-9. PMID: 4289172
7. Intracranial fibroblastic neoplasms in the hamster from bovine papilloma virus.  |  Robl, MG., et al. 1972. Cancer Res. 32: 2221-5. PMID: 4343012
8. Genetic analysis of the bovine papillomavirus E2 transcriptional activation domain.  |  Breiding, DE., et al. 1996. Virology. 221: 34-43. PMID: 8661412
9. Functional interaction of the bovine papillomavirus E2 transactivation domain with TFIIB.  |  Yao, JM., et al. 1998. J Virol. 72: 1013-9. PMID: 9444994

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-BPV Antibody (5091) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

BPV Antibody (5091) Specifications

Alternate Product Name: BPV

Product Clone Name: 5091

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: BPV

Epitope Species: bovine papillomavirus

Product Reactivity/Detection: BPV

Species Reactivity/Detection: NSR

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: ELISA

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for BPV Antibody (5091): N/A