Date published: 2025-12-19

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Boc-Sar-OH (CAS 13734-36-6)

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Alternate Names:
Boc-N-methylglycine; Boc-sarcosine
CAS Number:
13734-36-6
Molecular Weight:
189.21
Molecular Formula:
C8H15NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Boc-Sar-OH is a compound that functions as a protecting group for amino acids in peptide synthesis. It acts by temporarily blocking the reactive functional groups of amino acids, allowing for selective reactions to occur at specific sites within the peptide chain. Boc-Sar-Oh plays a role in controlling the sequence and structure of peptides during the synthesis process. Boc-Sar-OH interacts at the molecular level by forming stable covalent bonds with the amino acid side chains, preventing unwanted reactions and ensuring the desired peptide bond formation. Its mechanism of action involves the reversible attachment and detachment of the protecting group, enabling precise manipulation of the peptide′s chemical structure.


Boc-Sar-OH (CAS 13734-36-6) References

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  2. Novel prodrugs of SN38 using multiarm poly(ethylene glycol) linkers.  |  Zhao, H., et al. 2008. Bioconjug Chem. 19: 849-59. PMID: 18370417
  3. Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 6 (STAT6) with Cell-Permeable, Phosphatase-Stable Phosphopeptide Mimics Potently Inhibits Tyr641 Phosphorylation and Transcriptional Activity.  |  Mandal, PK., et al. 2015. J Med Chem. 58: 8970-84. PMID: 26506089
  4. Nα-Amino acid containing privileged structures: design, synthesis and use in solid-phase peptide synthesis.  |  Schütznerová, E., et al. 2018. Org Biomol Chem. 16: 5359-5362. PMID: 30014064
  5. Synthesis and Antimicrobial Activity of Phosphonopeptide Derivatives Incorporating Single and Dual Inhibitors.  |  Ng, KT., et al. 2020. Molecules. 25: PMID: 32231126
  6. Zelkovamycin is an OXPHOS Inhibitory Member of the Argyrin Natural Product Family.  |  Krahn, D., et al. 2020. Chemistry. 26: 8524-8531. PMID: 32250484
  7. Total synthesis of biseokeaniamides A-C and late-stage electrochemically-enabled peptide analogue synthesis.  |  Lin, Y. and Malins, LR. 2020. Chem Sci. 11: 10752-10758. PMID: 34094328
  8. Use of BOP-Cl in the presence of Boc-amino monothioacids for the thioacylation of imino acid residues.  |  Le, HT., et al. 1996. Bioorg Med Chem. 4: 2201-9. PMID: 9022983
  9. Simultaneous activation of two different receptor systems by enkephalin/neurotensin conjugates having spacer chains of various lengths.  |  Yano, K., et al. 1998. Eur J Pharm Sci. 7: 41-48. PMID: 9845776

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Boc-Sar-OH, 5 g

sc-227496
5 g
$21.00