Date published: 2025-9-6

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Boc-Met-Leu-Phe-OH (CAS 67247-12-5)

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CAS Number:
67247-12-5
Purity:
≥95%
Molecular Weight:
509.67
Molecular Formula:
C25H39N3O6S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Boc-Met-Leu-Phe-OH functions as a substrate in enzymatic assays and receptor binding studies. It acts as a competitive inhibitor of certain enzymes and receptors, interfering with their normal function. Boc-Met-Leu-Phe-Oh is known to interact with specific binding sites, altering the activity of the target molecules. Boc-Met-Leu-Phe-OH modulates the activity of enzymes and receptors by binding to their active sites or allosteric sites, thereby affecting their catalytic or signaling functions. Boc-Met-Leu-Phe-Oh is used to investigate the molecular mechanisms of enzyme activity and receptor signaling pathways in various experimental models. Its mechanism of action involves specific interactions with target molecules, leading to changes in their biochemical activity and cellular responses. Boc-Met-Leu-Phe-OH is valuable for studying the molecular interactions and regulatory processes involved in enzyme function and receptor signaling.


Boc-Met-Leu-Phe-OH (CAS 67247-12-5) References

  1. Determination of the cyclic depsipeptide FK228 in human and mouse plasma by liquid chromatography with mass-spectrometric detection.  |  Chen, X., et al. 2008. J Chromatogr B Analyt Technol Biomed Life Sci. 865: 153-8. PMID: 18342585
  2. Diastereoselective hydrolysis of peptide esters by alkaline protease. Preparation of racemization-free peptides.  |  Chen, ST., et al. 1991. Int J Pept Protein Res. 37: 347-50. PMID: 1894450
  3. The main functions and structural modifications of tripeptide N-formyl-methionyl-leucyl-phenylalanine (fMLP) as a chemotactic factor.  |  Yang, KH., et al. 2008. Pharmazie. 63: 779-83. PMID: 19069235
  4. Short one-pot chemo-enzymatic synthesis of L-lysine and L-alanine diblock co-oligopeptides.  |  Fagerland, J., et al. 2014. Biomacromolecules. 15: 735-43. PMID: 24484289
  5. The role of formylated peptides and formyl peptide receptor 1 in governing neutrophil function during acute inflammation.  |  Dorward, DA., et al. 2015. Am J Pathol. 185: 1172-84. PMID: 25791526
  6. Evaluation of CYP3A-mediated drug-drug interactions with romidepsin in patients with advanced cancer.  |  Laille, E., et al. 2015. J Clin Pharmacol. 55: 1378-85. PMID: 26053962
  7. Synthetic strategies toward 1,3-oxathiolane nucleoside analogues.  |  Aher, UP., et al. 2021. Beilstein J Org Chem. 17: 2680-2715. PMID: 34804240
  8. [Synthetic tripeptides as chemotaxins or chemotaxin antagonists (author's transl)].  |  Fruchtmann, R., et al. 1981. Hoppe Seylers Z Physiol Chem. 362: 163-74. PMID: 7216170
  9. Further studies on the structural requirements for synthetic peptide chemoattractants.  |  Freer, RJ., et al. 1980. Biochemistry. 19: 2404-10. PMID: 7387981

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Boc-Met-Leu-Phe-OH, 100 mg

sc-293900
100 mg
$140.00

Boc-Met-Leu-Phe-OH, 250 mg

sc-293900A
250 mg
$340.00