Boc-Gln-D-Trp(Formyl)-Phe benzyl ester trifluoroacetate salt
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Boc-Gln-D-Trp(Formyl)-Phe benzyl ester trifluoroacetate salt is a Substance P antagonist derived from glutaminyl-D-tryptophylphenylalanine. Substance P is a neuropeptide, a type of signaling molecule found in the nervous system. It plays a role in various physiological processes and is primarily known for its involvement in pain transmission and neurogenic inflammation. Boc-Gln-D-Trp(Formyl)-Phe benzyl ester trifluoroacetate salt is often used as a building block or intermediate in the synthesis of peptides. Its Boc protecting group safeguards the amino group, and the specific amino acid sequence and ester linkage contribute to the desired peptide structure. The trifluoroacetate salt form aids in solubility and stability during synthesis or subsequent experimental procedures.
Boc-Gln-D-Trp(Formyl)-Phe benzyl ester trifluoroacetate salt References
- Studies on neurokinin antagonists. 1. The design of novel tripeptides possessing the glutaminyl-D-tryptophylphenylalanine sequence as substance P antagonists. | Hagiwara, D., et al. 1992. J Med Chem. 35: 2015-25. PMID: 1375965
- Lithocholic Acid Activates Mas-Related G Protein-Coupled Receptors, Contributing to Itch in Mice. | Song, MH. and Shim, WS. 2022. Biomol Ther (Seoul). 30: 38-47. PMID: 34263729
- Peripheral endomorphins drive mechanical alloknesis under the enzymatic control of CD26/DPPIV. | Komiya, E., et al. 2022. J Allergy Clin Immunol. 149: 1085-1096. PMID: 34411589
- Chlorogenic Acid Isomers Isolated from Artemisia lavandulaefolia Exhibit Anti-Rosacea Effects In Vitro. | Roh, KB., et al. 2022. Biomedicines. 10: PMID: 35203672
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Boc-Gln-D-Trp(Formyl)-Phe benzyl ester trifluoroacetate salt, 25 mg | sc-300285 | 25 mg | $426.00 |