BML-260 (CAS 101439-76-3)
See product citations (1)
QUICK LINKS
BML-260 is a synthetic compound recognized for its role as an inhibitor of dipeptidyl peptidase III (DPP-III), a zinc-dependent enzyme that is part of the M49 peptidase family. In research, BML-260 is used to investigate the enzymatic activity of DPP-III and its contribution to the metabolism of bioactive peptides. Studies involving BML-260 help elucidate the physiological function of DPP-III in processes such as pain modulation, immune response, and blood pressure regulation, given the enzyme′s role in the degradation of neuropeptides and hormones. By inhibiting DPP-III, researchers are able to assess the impact of this enzyme on cellular signaling pathways and explore its potential as a target for modulating the bioavailability of peptide hormones.
BML-260 (CAS 101439-76-3) References
- Repression of the expression of PPP3CC by ZEB1 confers activation of NF-κB and contributes to invasion and growth in glioma cells. | Wang, H., et al. 2018. Jpn J Clin Oncol. 48: 175-183. PMID: 29294030
- Therapeutic Chemical Screen Identifies Phosphatase Inhibitors to Reconstitute PKB Phosphorylation and Cardiac Contractility in ILK-Deficient Zebrafish. | Pott, A., et al. 2018. Biomolecules. 8: PMID: 30463267
- Identification of a rhodanine derivative BML-260 as a potent stimulator of UCP1 expression. | Feng, Z., et al. 2019. Theranostics. 9: 3501-3514. PMID: 31281493
- Genome-Wide Transcriptomic Analysis of Non-Tumorigenic Tissues Reveals Aging-Related Prognostic Markers and Drug Targets in Renal Cell Carcinoma. | Oh, E., et al. 2021. Cancers (Basel). 13: PMID: 34207247
- BML-260 promotes the growth of cord blood and mobilized peripheral blood hematopoietic stem and progenitor cells with improved reconstitution ability. | Albayrak, E., et al. 2022. J Cell Biochem. 123: 2009-2029. PMID: 36070493
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BML-260, 10 mg | sc-223822 | 10 mg | $143.00 |