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Bisindolylmaleimide II is a general inhibitor of all PKC (protein kinase C) subtypes. This compound also inhibits PDK1 (IC50 = 14 μM), which is an important kinase in the insulin signaling pathway.
See how others have used Bisindolylmaleimide II. Click on the entry to view the PubMed entry .
PMID: # 28039020 Abdelnabi, R. et al. 2017. Antiviral Res. 139: 79-87.
PMID: # 27660555 Ruedel, A. et al. 2016. Cancer Cell Int. 16: 71.
PMID: # 25087184 Limm, K. et al. 2014. Eur. J. Cancer. 50: 2714-24.
PMID: # 22228808 Diraimondo, TR. et al. 2012. J. Pharmacol. Exp. Ther. 341: 104-14.
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