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Bis(4-methylumbelliferyl)phosphate (CAS 51379-07-8)

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Alternate Names:
Bis(MU)-phos
CAS Number:
51379-07-8
Purity:
≥95%
Molecular Weight:
414.31
Molecular Formula:
C20H15O8P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Bis(4-methylumbelliferyl)phosphate (BMUP) is a compound used in a variety of scientific research applications. It is a fluorescent compound that is employed to study the mechanism of action and biochemical and physiological effects of various substances. Bis(4-methylumbelliferyl)phosphate serves as a substrate for various enzymes like phosphatases, phosphodiesterases, and kinases, as well as hormones including insulin, glucagon, and growth hormone.


Bis(4-methylumbelliferyl)phosphate (CAS 51379-07-8) References

  1. Bis-(4-methylumbelliferyl) phosphate as a substrate for the surface membrane-associated phosphodiesterase activity of pig platelets.  |  Taylor, DG., et al. 1977. Biochim Biophys Acta. 465: 667-71. PMID: 13836
  2. Variation in pH optima of hydrolytic enzyme activities in tropical rain forest soils.  |  Turner, BL. 2010. Appl Environ Microbiol. 76: 6485-93. PMID: 20709838
  3. Soluble sphingomyelinase from human urine as antigen for obtaining anti-sphingomyelinase antibodies.  |  Weitz, G., et al. 1985. Biochim Biophys Acta. 838: 92-7. PMID: 2981569
  4. Solid-phase assay for the detection of low-abundance enzymes, and antibodies to enzymes in immune reactions, using acid sphingomyelinase as a model.  |  Freeman, SJ., et al. 1984. Anal Biochem. 141: 248-52. PMID: 6093623
  5. Partial purification and properties of acid sphingomyelinase from rat liver.  |  Watanabe, K., et al. 1983. J Lipid Res. 24: 596-603. PMID: 6192193
  6. Purification of sphingomyelinase to apparent homogeneity by using hydrophobic chromatography.  |  Jones, CS., et al. 1981. Biochem J. 195: 373-82. PMID: 6274305
  7. Studies on sphingomyelinase and beta-glucosidase activities in Niemann-Pick disease variants. Phosphodiesterase activities measured with natural and artificial substrates.  |  Besley, GT. and Moss, SE. 1983. Biochim Biophys Acta. 752: 54-64. PMID: 6303436
  8. Chromatofocusing of skin fibroblast sphingomyelinase: alterations in Niemann-Pick disease type C shared by GM1-gangliosidosis.  |  Vanier, MT., et al. 1983. Clin Chim Acta. 130: 155-61. PMID: 6307547
  9. The active site of lysosomal sphingomyelinase: evidence for the involvement of hydrophobic and ionic groups.  |  Callahan, JW., et al. 1983. J Neurosci Res. 10: 151-63. PMID: 6313952
  10. Sphingomyelinase and nonspecific phosphodiesterase activities in Epstein-Barr virus-transformed lymphoid cell lines from Niemann-Pick disease A, B and C.  |  Levade, T., et al. 1984. Biochim Biophys Acta. 793: 321-4. PMID: 6324871

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bis(4-methylumbelliferyl)phosphate, 250 mg

sc-280624
250 mg
$255.00

Bis(4-methylumbelliferyl)phosphate, 500 mg

sc-280624A
500 mg
$459.00