Molecular structure of Bioallethrin, CAS Number: 22431-63-6
Bioallethrin (CAS 22431-63-6)
Alternate Names:
D-trans-Allethrin, (S)-3-Allyl-2-methyl-4-oxocyclopent-2-enyl-(1R,3R)-2,2-dimethyl-3-(2-methyl-prop-1-enyl)cyclopropancarboxylate
Application:
Bioallethrin is a potent calcineurin (protein phosphatase 2B) inhibitor
CAS Number:
22431-63-6
Molecular Weight:
302.4
Molecular Formula:
C19H26O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Although bioallethrin is a type I pyrethroid, its effects on calcineurin (protein phosphatase 2B) resembles those of type II pyrethrins. Unlike most type I pyrethrins, which are very weak, bioallethrin is a potent calcineurin inhibitor.
Bioallethrin (CAS 22431-63-6) References
- Specific inhibition of calcineurin by type II synthetic pyrethroid insecticides. | Enan, E. and Matsumura, F. 1992. Biochem Pharmacol. 43: 1777-84. PMID: 1315545
- Neurotoxic effects of two different pyrethroids, bioallethrin and deltamethrin, on immature and adult mice: changes in behavioral and muscarinic receptor variables. | Eriksson, P. and Fredriksson, A. 1991. Toxicol Appl Pharmacol. 108: 78-85. PMID: 2006507
- Effects of two pyrethroids, bioallethrin and deltamethrin, on subpopulations of muscarinic and nicotinic receptors in the neonatal mouse brain. | Eriksson, P. and Nordberg, A. 1990. Toxicol Appl Pharmacol. 102: 456-63. PMID: 2315914
- A capillary micellar electrokinetic chromatography method for the stereoselective quantitation of bioallethrin in biotic and abiotic samples. | García, MÁ., et al. 2017. J Chromatogr A. 1510: 108-116. PMID: 28648257
- Bioallethrin enhances generation of ROS, damages DNA, impairs the redox system and causes mitochondrial dysfunction in human lymphocytes. | Arif, A., et al. 2021. Sci Rep. 11: 8300. PMID: 33859309
- Bioallethrin activates specific olfactory sensory neurons and elicits spatial repellency in Aedes aegypti. | Valbon, W., et al. 2022. Pest Manag Sci. 78: 438-445. PMID: 34661374
- Interaction of the insecticide bioallethrin with human hemoglobin: biophysical, in silico and enzymatic studies. | Arif, A., et al. 2023. J Biomol Struct Dyn. 41: 6591-6602. PMID: 35950518
- Esculin protects human blood cells from bioallethrin-induced toxicity: An ex vivo study. | Arif, A., et al. 2023. Pestic Biochem Physiol. 191: 105375. PMID: 36963944
- AsOBP1 is required for bioallethrin repellency in the malaria vector mosquito Anopheles sinensis. | Zhang, Y., et al. 2024. Insect Sci.. PMID: 38389031
- Bioallethrin causes permanent changes in behavioural and muscarinic acetylcholine receptor variables in adult mice exposed neonatally to DDT. | Johansson, U., et al. 1995. Eur J Pharmacol. 293: 159-66. PMID: 7589230
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bioallethrin, 25 mg | sc-202501 | 25 mg | $62.00 | |||
Bioallethrin, 100 mg | sc-202501A | 100 mg | $185.00 |