Betaine-d3 Hydrochloride (CAS 1219349-47-9)
QUICK LINKS
Betaine-d3 hydrochloride is a deuterated form of betaine hydrochloride, used as an isotopic labeling compound in analytical chemistry. It serves as an internal standard for nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry, aiding in the precise quantification of betaine in complex biological samples. The presence of deuterium atoms in betaine-d3 hydrochloride makes it an invaluable tool in studies focusing on the metabolism and biological pathways of betaine, as its behavior closely mirrors the non-deuterated form while allowing for differentiation based on its isotopic mass. This compound is particularly useful in research studying osmoregulation and methyl group metabolism, as betaine plays a role in both of these processes. Additionally, betaine-d3 hydrochloride is used in environmental and food sciences to trace and measure betaine content in various samples, contributing to the understanding of its distribution and role outside biological systems.
Betaine-d3 Hydrochloride (CAS 1219349-47-9) References
- Choline intakes exceeding recommendations during human lactation improve breast milk choline content by increasing PEMT pathway metabolites. | Davenport, C., et al. 2015. J Nutr Biochem. 26: 903-11. PMID: 26025328
- Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control. | Mueller, DM., et al. 2015. Atherosclerosis. 243: 638-44. PMID: 26554714
- Intra-individual variation of plasma trimethylamine-N-oxide (TMAO), betaine and choline over 1 year. | Kühn, T., et al. 2017. Clin Chem Lab Med. 55: 261-268. PMID: 27447240
- Metabolic products of the intestinal microbiome and extremes of atherosclerosis. | Bogiatzi, C., et al. 2018. Atherosclerosis. 273: 91-97. PMID: 29702430
- Mediterranean Diet Score: Associations with Metabolic Products of the Intestinal Microbiome, Carotid Plaque Burden, and Renal Function. | Pignanelli, M., et al. 2018. Nutrients. 10: PMID: 29914158
- Moderate Renal Impairment and Toxic Metabolites Produced by the Intestinal Microbiome: Dietary Implications. | Pignanelli, M., et al. 2019. J Ren Nutr. 29: 55-64. PMID: 30100156
- Effects of abomasal infusions of fatty acids and one-carbon donors on hepatic ceramide and phosphatidylcholine in lactating Holstein dairy cows. | Myers, WA., et al. 2019. J Dairy Sci. 102: 7087-7101. PMID: 31178188
- Dietary Whole Egg Reduces Body Weight Gain in a Dose-Dependent Manner in Zucker Diabetic Fatty Rats. | Saande, CJ., et al. 2019. J Nutr. 149: 1766-1775. PMID: 31254347
- Fast LC-ESI-MS/MS analysis and influence of sampling conditions for gut metabolites in plasma and serum. | van der Laan, T., et al. 2019. Sci Rep. 9: 12370. PMID: 31451722
- Targeted ultra-performance liquid chromatography/tandem mass spectrometric quantification of methylated amines and selected amino acids in biofluids. | Roggensack, T., et al. 2020. Rapid Commun Mass Spectrom. 34: e8646. PMID: 31674086
- Robotic automation of a UHPLC/MS-MS method profiling one-carbon metabolites, amino acids, and precursors in plasma. | Andraos, S., et al. 2020. Anal Biochem. 592: 113558. PMID: 31911045
- Maternal Plasma Betaine in Middle Pregnancy Was Associated with Decreased Risk of GDM in Twin Pregnancy: A Cohort Study. | Gong, X., et al. 2021. Diabetes Metab Syndr Obes. 14: 2495-2504. PMID: 34113141
- Trimethylamine-N-Oxide and Precursors as Novel Potential Biomarkers for Anxiety Disorder. | Le, J., et al. 2022. Lab Med. 53: 177-182. PMID: 34480186
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Betaine-d3 Hydrochloride, 2.5 mg | sc-217747 | 2.5 mg | $377.00 | |||
Betaine-d3 Hydrochloride, 5 mg | sc-217747A | 5 mg | $637.00 | |||
Betaine-d3 Hydrochloride, 10 mg | sc-217747B | 10 mg | $1082.00 | |||
Betaine-d3 Hydrochloride, 25 mg | sc-217747C | 25 mg | $2346.00 |