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β-Tocopherol (CAS 16698-35-4)

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Alternate Names:
(R)-2,5,8-Trimethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-ol
Application:
β-Tocopherol is a naturally occurring forms of Vitamin E that is biologically less active than α-Tocopherol
CAS Number:
16698-35-4
Molecular Weight:
416.68
Molecular Formula:
C28H48O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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β-Tocopherol is a form of vitamin E that is found in various dietary sources and is of interest in nutritional and biochemical research. It is one of the eight naturally occurring isomers of vitamin E. Studies involving β-Tocopherol focus on its capacity to scavenge free radicals, thereby protecting cell membranes from oxidative damage. In food science, research on β-Tocopherol examines its stability during food processing and storage, as well as its impact on the shelf life and nutritional quality of food products. Additionally, β-Tocopherol is investigated for its role in modulating signaling pathways and gene expression related to oxidative stress. Its presence in natural systems and its interactions with other forms of vitamin E are also key areas of study, contributing to a broader understanding of antioxidant mechanisms and nutritional science.


β-Tocopherol (CAS 16698-35-4) References

  1. Alpha-tocopherol decreases interleukin-1 beta release from activated human monocytes by inhibition of 5-lipoxygenase.  |  Devaraj, S. and Jialal, I. 1999. Arterioscler Thromb Vasc Biol. 19: 1125-33. PMID: 10195945
  2. Differential inhibition by alpha- and beta-tocopherol of human erythroleukemia cell adhesion: role of integrins.  |  Breyer, I. and Azzi, A. 2001. Free Radic Biol Med. 30: 1381-9. PMID: 11390183
  3. Brain tumor and role of beta-carotene, a-tocopherol, superoxide dismutase and glutathione peroxidase.  |  Aggarwal, S., et al. 2006. J Cancer Res Ther. 2: 24-7. PMID: 17998669
  4. Distribution of alpha-, gamma (+beta)- and delta-tocopherol in the seminal plasma, spermatozoa and seminal vesicles of rabbit.  |  Mourvaki, E., et al. 2008. Andrologia. 40: 282-5. PMID: 18811917
  5. Dietary marine-derived tocopherol has a higher biological availability in mice relative to alpha-tocopherol.  |  Gotoh, N., et al. 2009. Lipids. 44: 133-43. PMID: 18989718
  6. Replacement of alpha-tocopherol by beta-tocopherol enhances resistance to photooxidative stress in a xanthophyll-deficient strain of Chlamydomonas reinhardtii.  |  Sirikhachornkit, A., et al. 2009. Eukaryot Cell. 8: 1648-57. PMID: 19717743
  7. The effect of β-carotene on lumbar osteophyte formation.  |  Imagama, S., et al. 2011. Spine (Phila Pa 1976). 36: 2293-8. PMID: 21673632
  8. Determination of tocopherol contents of some olive varieties harvested at different ripening periods.  |  Dağdelen, A., et al. 2012. Nat Prod Res. 26: 1454-7. PMID: 21859374
  9. Fatty acid composition and tocopherol profiles of safflower (Carthamus tinctorius L.) seed oils.  |  Matthaus, B., et al. 2015. Nat Prod Res. 29: 193-6. PMID: 25329876
  10. Deep eutectic solvent-based liquid-phase microextraction coupled with reversed-phase high-performance liquid chromatography for determination of α-, β-, γ-, and δ-tocopherol in edible oils.  |  Xie, Q., et al. 2021. Anal Bioanal Chem. 413: 577-584. PMID: 33205254
  11. Functional Differentiation of BnVTE4 Gene Homologous Copies in α-Tocopherol Biosynthesis Revealed by CRISPR/Cas9 Editing.  |  Zhang, H., et al. 2022. Front Plant Sci. 13: 850924. PMID: 35481148
  12. QTL and Candidate Genes for Seed Tocopherol Content in 'Forrest' by 'Williams 82' Recombinant Inbred Line (RIL) Population of Soybean.  |  Knizia, D., et al. 2022. Plants (Basel). 11: PMID: 35567259
  13. The effect of alpha-tocopherol and beta-tocopherol on proliferation, protein kinase C activity and gene expression in different cell lines.  |  Fazzio, A., et al. 1997. Biochem Mol Biol Int. 41: 93-101. PMID: 9043639
  14. Molecular basis of alpha-tocopherol control of smooth muscle cell proliferation.  |  Azzi, A., et al. 1998. Biofactors. 7: 3-14. PMID: 9523023
  15. Alpha-tocopherol but not beta-tocopherol inhibits thrombin-induced PKC activation and endothelin secretion in endothelial cells.  |  Martin-Nizard, F., et al. 1998. J Cardiovasc Risk. 5: 339-45. PMID: 9920007

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

β-Tocopherol, 25 mg

sc-471187
25 mg
$580.00

β-Tocopherol, 250 mg

sc-471187A
250 mg
$4386.00