Date published: 2026-3-13

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Benzothiazole (CAS 95-16-9)

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CAS Number:
95-16-9
Molecular Weight:
135.19
Molecular Formula:
C7H5NS
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Benzothiazole, a heterocyclic aromatic compound containing a sulfur atom within its ring structure, holds significance as an intermediate in the synthesis of organic compounds. With their versatility and diverse range of applications, benzothiazoles have been extensively employed in scientific research. They have played a role in the synthesis of polymers, polysaccharides, and inorganic compounds. Furthermore, benzothiazoles have found application in the synthesis of metal complexes, organic catalysts, and natural products. The precise mechanism of action of benzothiazoles remains incompletely understood. However, it is hypothesized that they interact with proteins and enzymes within the cell, thereby influencing their activity. Additionally, benzothiazoles can act as electron acceptors, thus influencing the cell′s energy metabolism.


Benzothiazole (CAS 95-16-9) References

  1. Development of benzothiazole 'click-on' fluorogenic dyes.  |  Qi, J. and Tung, CH. 2011. Bioorg Med Chem Lett. 21: 320-3. PMID: 21111622
  2. Benzothiazole toxicity assessment in support of synthetic turf field human health risk assessment.  |  Ginsberg, G., et al. 2011. J Toxicol Environ Health A. 74: 1175-83. PMID: 21797770
  3. Benzotriazole, benzothiazole, and benzophenone compounds in indoor dust from the United States and East Asian countries.  |  Wang, L., et al. 2013. Environ Sci Technol. 47: 4752-9. PMID: 23544437
  4. The washout effect during laundry on benzothiazole, benzotriazole, quinoline, and their derivatives in clothing textiles.  |  Luongo, G., et al. 2016. Environ Sci Pollut Res Int. 23: 2537-48. PMID: 26429136
  5. Effects of the microbial secondary metabolite benzothiazole on the nutritional physiology and enzyme activities of Bradysia odoriphaga (Diptera: Sciaridae).  |  Zhao, Y., et al. 2016. Pestic Biochem Physiol. 129: 49-55. PMID: 27017881
  6. A novel benzothiazole-based fluorescent probe for cysteine detection and its application on test paper and in living cells.  |  Yu, Y., et al. 2018. Talanta. 176: 151-155. PMID: 28917734
  7. Synthesis, characterization and biological screening of pyrazole-conjugated benzothiazole analogs.  |  Bhat, M. and Belagali, SL. 2018. Future Med Chem. 10: 71-87. PMID: 29235357
  8. Occurrence of benzothiazole and its derivates in tire wear, road dust, and roadside soil.  |  Zhang, J., et al. 2018. Chemosphere. 201: 310-317. PMID: 29525659
  9. Chemicals from textiles to skin: an in vitro permeation study of benzothiazole.  |  Iadaresta, F., et al. 2018. Environ Sci Pollut Res Int. 25: 24629-24638. PMID: 29911295
  10. Benzothiazole inhibits the growth of Phytophthora capsici through inducing apoptosis and suppressing stress responses and metabolic detoxification.  |  Mei, X., et al. 2019. Pestic Biochem Physiol. 154: 7-16. PMID: 30765059
  11. Amoebicidal activity of benzothiazole on Acanthamoeba castellanii cysts and trophozoites and its cytotoxic potentials.  |  Ozpinar, N., et al. 2020. Acta Trop. 203: 105322. PMID: 31887263
  12. Determination of benzotriazole and benzothiazole derivatives in marketed fish by double-vortex-ultrasonic assisted matrix solid-phase dispersion and ultrahigh-performance liquid chromatography-high resolution mass spectrometry.  |  Chen, CH., et al. 2020. Food Chem. 333: 127516. PMID: 32683261
  13. Comparative Analysis of Botrytis cinerea in Response to the Microbial Secondary Metabolite Benzothiazole Using iTRAQ-Based Quantitative Proteomics.  |  Cui, K., et al. 2021. Phytopathology. 111: 1313-1326. PMID: 33325724
  14. Hybrid Materials Based on Magnetic Iron Oxides with Benzothiazole Derivatives: A Plausible Potential Spectroscopy Probe.  |  Corrêa, S., et al. 2021. Int J Mol Sci. 22: PMID: 33921510
  15. Enantiomeric profiling of a chiral benzothiazole necroptosis inhibitor.  |  Zhu, J., et al. 2021. Bioorg Med Chem Lett. 43: 128084. PMID: 33964444

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Benzothiazole, 5 g

sc-254959
5 g
$42.00

Benzothiazole, 100 g

sc-254959A
100 g
$68.00