Molecular structure of Bambuterol Hydrochloride, CAS Number: 81732-46-9
Bambuterol Hydrochloride (CAS 81732-46-9)
Alternate Names:
KWD-2183; Bambec
Application:
Bambuterol Hydrochloride is an inhibitor of plasma cholinesterase during metabolism
CAS Number:
81732-46-9
Purity:
≥98%
Molecular Weight:
403.91
Molecular Formula:
C18H29N3O5•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Bambuterol Hydrochloride is a chemical compound extensively used in various research disciplines for its biochemical properties as a precursor of terbutaline. In the field of pharmacokinetics, it is studied to understand the enzymatic conversion processes that activate precursory chemicals into their pharmacologically active forms. Researchers are interested in the compound′s metabolism and stability, as it provides insights into the design of systems that optimize the bioavailability of active substances. Additionally, this compound has a role in analytical research, where it is used as a reference standard to calibrate equipment and validate methods for detecting the presence and concentration of related substances in various sample matrices.
Bambuterol Hydrochloride (CAS 81732-46-9) References
- Quantification of bambuterol hydrochloride in a formulated product using solid-state NMR. | Harris, RK., et al. 2005. J Pharm Biomed Anal. 38: 858-64. PMID: 15869858
- Mechanism of action of bambuterol: a beta-agonist prodrug with sustained lung affinity. | Svensson, LA. 1991. Agents Actions Suppl. 34: 71-8. PMID: 1686529
- Effects of bambuterol and terbutaline on isolated rat's tracheal smooth muscle. | Chou, YL., et al. 2010. Eur Arch Otorhinolaryngol. 267: 1305-11. PMID: 20012638
- Determination of Montelukast Sodium and Bambuterol Hydrochloride in Tablets using RP HPLC. | Patil, S., et al. 2009. Indian J Pharm Sci. 71: 58-61. PMID: 20177459
- Development and Validation of a Rapid RP-UPLC Method for the Simultaneous Estimation of Bambuterol Hydrochloride and Montelukast Sodium from Tablets. | Yanamandra, R., et al. 2012. Indian J Pharm Sci. 74: 116-21. PMID: 23325991
- Stereoselective inhibition of human butyrylcholinesterase by the enantiomers of bambuterol and their intermediates. | Pistolozzi, M., et al. 2015. Drug Metab Dispos. 43: 344-52. PMID: 25504505
- Chiral analysis of bambuterol, its intermediate and active drug in human plasma by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study. | Zhou, T., et al. 2015. J Chromatogr B Analyt Technol Biomed Life Sci. 997: 38-44. PMID: 26092775
- Design, synthesis and biological evaluation of bambuterol analogues as novel inhibitors of butyrylcholinesterase. | Wu, J., et al. 2017. Eur J Med Chem. 126: 61-71. PMID: 27744187
- Bambuterol: uptake and metabolism in guinea pig isolated lungs. | Ryrfeldt, A., et al. 1988. Pharm Res. 5: 151-5. PMID: 3244626
- Quick simultaneous analysis of bambuterol and montelukast based on synchronous spectrofluorimetric technique. | El Gamal, R., et al. 2020. R Soc Open Sci. 7: 201156. PMID: 33489270
- (RS)-bambuterol and its enantiomers: Potential improvement of (R)-bambuterol in mice with colitis. | Deng, L., et al. 2022. Int Immunopharmacol. 103: 108501. PMID: 34974400
- Bambuterol and terbutaline in human cerebrospinal fluid and plasma. | Rosberg, B., et al. 1993. Eur J Clin Pharmacol. 45: 147-50. PMID: 8223836
- Clinical pharmacokinetics of bambuterol. | Sitar, DS. 1996. Clin Pharmacokinet. 31: 246-56. PMID: 8896942
Inhibitor of:
BChE.Activator of:
beta2-AR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bambuterol Hydrochloride, 5 mg | sc-205598B | 5 mg | $64.00 | |||
Bambuterol Hydrochloride, 250 mg | sc-205598C | 250 mg | $158.00 | |||
Bambuterol Hydrochloride, 500 mg | sc-205598 | 500 mg | $315.00 | |||
Bambuterol Hydrochloride, 1 g | sc-205598A | 1 g | $338.00 | |||
Bambuterol Hydrochloride, 5 g | sc-205598D | 5 g | $885.00 |