BADIG (CAS 50605-12-4)

BADIG (short for bis(4-azidobenzyl)diethylene glycol) is a chemical compound that has been widely used in scientific research, particularly in the field of bioconjugation and click chemistry. It consists of diethylene glycol functionalized with azido groups on both ends. BADIG serves as a valuable tool for the modification and functionalization of biomolecules. Its azido groups readily participate in click reactions, specifically copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), enabling efficient and bioorthogonal coupling with other molecules. Researchers have employed BADIG for the site-specific labeling of proteins, peptides, and nucleic acids. Its unique reactivity and stability allow for the conjugation of various reporter molecules, such as fluorophores, biotin, or affinity tags, to biomolecules of interest. Furthermore, BADIG has been utilized in the development of nanomaterials, surface modifications, and biofunctionalization strategies. The versatility of BADIG in bioconjugation has enabled the synthesis of multifunctional constructs for applications in bioimaging, drug delivery, and diagnostic assays. Moreover, BADIG has been employed in the construction of complex biomolecular architectures and the fabrication of bioactive surfaces. The research applications of BADIG contribute to advancements in chemical biology, bioconjugation techniques, and the development of innovative tools for biomolecule modification and functionalization.