Molecular structure of Azetidine-2-carboxylic acid, CAS Number: 2517-04-6
Azetidine-2-carboxylic acid (CAS 2517-04-6)
See product citations (3)
CAS Number:
2517-04-6
Molecular Weight:
101.105
Molecular Formula:
C4H7NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Azetidine-2-carboxylic acid (A2CA) belongs to the azetidine compound family and serves as a vital organic compound. This colorless, water-soluble solid finds extensive use in laboratory applications as a chiral building block and a reagent for organic synthesis. It plays a significant role in the creation of fatty acids, proteins, and peptides, where it acts as a catalyst. Furthermore, Azetidine-2-carboxylic acid is associated with the regulation of gene expression due to its ability to bind to both DNA and RNA.
Azetidine-2-carboxylic acid (CAS 2517-04-6) References
- Effects of azetidine-2-carboxylic acid on treatments of hepatoma cells with single or fractionated X-ray irradiations and on thermal radiosensitization in normal and thermotolerant cells. | van Rijn, J., et al. 1999. Radiat Oncol Investig. 7: 270-7. PMID: 10580896
- Heat shock response by cells treated with azetidine-2-carboxylic acid. | Van Rijn, J., et al. 2000. Int J Hyperthermia. 16: 305-18. PMID: 10949127
- A novel acetyltransferase found in Saccharomyces cerevisiae Sigma1278b that detoxifies a proline analogue, azetidine-2-carboxylic acid. | Shichiri, M., et al. 2001. J Biol Chem. 276: 41998-2002. PMID: 11555637
- [Determination of the azetidine-2-carboxylic acid from lily of the valley]. | Liu, H. 1999. Se Pu. 17: 410-2. PMID: 12552869
- Characterization of novel acetyltransferases found in budding and fission yeasts that detoxify a proline analogue, azetidine-2-carboxylic acid. | Nomura, M., et al. 2003. J Biochem. 133: 67-74. PMID: 12761200
- Azetidine-2-carboxylic acid: a new cyclic imino acid occurring in plants. | FOWDEN, L. 1956. Biochem J. 64: 323-32. PMID: 13363844
- Nitrogenous compounds and nitrogen metabolism in the Liliaceae. 5. The metabolism of azetidine-2-carboxylic acid. | FOWDEN, L. and BRYANT, M. 1959. Biochem J. 71: 210-7. PMID: 13628556
- Effect of azetidine 2-carboxylic Acid on ion uptake and ion release to the xylem of excised barley roots. | Pitman, MG., et al. 1977. Plant Physiol. 60: 240-6. PMID: 16660068
- Misincorporation of the proline analog azetidine-2-carboxylic acid in the pathogenesis of multiple sclerosis: a hypothesis. | Rubenstein, E. 2008. J Neuropathol Exp Neurol. 67: 1035-40. PMID: 18957898
- Highly efficient and enantioselective biotransformations of racemic azetidine-2-carbonitriles and their synthetic applications. | Leng, DH., et al. 2009. J Org Chem. 74: 6077-82. PMID: 19627128
- Inhibition of Arabidopsis growth by the allelopathic compound azetidine-2-carboxylate is due to the low amino acid specificity of cytosolic prolyl-tRNA synthetase. | Lee, J., et al. 2016. Plant J. 88: 236-246. PMID: 27332880
- Mutant cell lines resistant to azetidine-2-carboxylic acid: alterations in the synthesis of proline from glutamic acid. | Lodato, RF., et al. 1984. J Cell Physiol. 119: 137-43. PMID: 6142896
- Use of the L-proline analog, L-azetidine-2-carboxylic acid (LACA) to analyse embryonic growth and determination and expression of the chondrogenic phenotype in vivo and in vitro. | Hall, BK. 1978. Anat Rec. 190: 243-55. PMID: 629405
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Azetidine-2-carboxylic acid, 250 mg | sc-278714 | 250 mg | $87.00 |