ARG-Vasopressin Antibody (VAS 12-2-2): sc-73505

ARG-Vasopressin Antibody (VAS 12-2-2) is a mouse monoclonal IgG1 antibody that detects ARG-Vasopressin in human samples through enzyme-linked immunosorbent assay (ELISA). ARG-Vasopressin is a crucial antidiuretic hormone produced in the neurohypophysis, playing a vital role in maintaining body fluid homeostasis and regulating blood pressure. ARG-Vasopressin is primarily located in the hypothalamus and is secreted into the bloodstream, where ARG-Vasopressin interacts with specific receptors to exert physiological effects. ARG-Vasopressin presence in the bloodstream is tightly regulated by hypothalamic osmoreceptors, which respond to changes in plasma osmolality. This regulation is essential because excessive secretion can lead to increased mean arterial pressure and systemic vascular resistance, potentially resulting in cardiovascular complications. ARG-Vasopressin has been implicated in various pathological conditions, including certain cancers, where ARG-Vasopressin may act as an autocrine growth factor, promoting tumor growth through pathways such as ERK1/2 activation. ARG-Vasopressin′s ability to influence both vascular and renal functions underscores ARG-Vasopressin′s importance as a therapeutic target in conditions like acute and chronic heart failure, as well as ARG-Vasopressin′s potential role in managing migraines through antinociceptive properties. Anti-ARG-Vasopressin antibody (VAS 12-2-2) is an invaluable tool for researchers investigating the multifaceted roles of this hormone in health and disease.

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ARG-Vasopressin Antibody (VAS 12-2-2) References:

1. Arg-vasopressin increases proliferation of human osteoblast-like cells and decreases production of interleukin-6 and macrophage colony-stimulating factor.  |  Lagumdzija, A., et al. 2004. Regul Pept. 121: 41-8. PMID: 15256272
2. Local overexpression of V1a-vasopressin receptor enhances regeneration in tumor necrosis factor-induced muscle atrophy.  |  Costa, A., et al. 2014. Biomed Res Int. 2014: 235426. PMID: 24971321
3. Conformation and dynamics of 8-Arg-vasopressin in solution.  |  Haensele, E., et al. 2014. J Mol Model. 20: 2485. PMID: 25374389
4. Arg-vasopressin facilitates calcium channel currents in osteoblasts.  |  Hosokawa, S., et al. 2014. Bull Tokyo Dent Coll. 55: 241-4. PMID: 25477042
5. Microinjection of anti-vasopressin serum into hippocampus in mice: effects on appetitively reinforced task after intraventricular administration of Arg-vasopressin.  |  Alescio-Lautier, B., et al. 1989. Brain Res. 500: 287-94. PMID: 2605497
6. Increase in cytosolic calcium and phosphoinositide metabolism induced by angiotensin II and [Arg]vasopressin in vascular smooth muscle cells.  |  Nabika, T., et al. 1985. J Biol Chem. 260: 4661-70. PMID: 2985562
7. GC-MS and LC-MS/MS pilot studies on the guanidine (NG)-dimethylation in native, asymmetrically and symmetrically NG-dimethylated arginine-vasopressin peptides and proteins in human red blood cells.  |  Bollenbach, A., et al. 2020. J Chromatogr B Analyt Technol Biomed Life Sci. 1141: 122024. PMID: 32062367
8. Radioimmunoassay of arginine-vasopressin in human plasma: development and clinical application.  |  Hummerich, W., et al. 1983. Klin Wochenschr. 61: 203-8. PMID: 6843047
9. GABAergic control of Arg-vasopressin release from suprachiasmatic nucleus slice culture.  |  Isobe, Y. and Nishino, H. 1997. Brain Res. 755: 213-20. PMID: 9175889
10. Circadian rhythm of Arg-vasopressin contents in the suprachiasmatic nucleus in relation to corticosterone.  |  Isobe, Y. and Isobe, M. 1998. Brain Res. 800: 78-85. PMID: 9685591

The preferred ARG-Vasopressin antibody is ARG-Vasopressin Antibody (VAS 10-2-2): sc-73504.