α-Hydroxy montelukast (CAS 2045402-27-3)
Alternate Names:
[1-[1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropyl](hydroxy)acetic Acid
CAS Number:
2045402-27-3
Molecular Weight:
602.18
Molecular Formula:
C35H36ClNO4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
α-Hydroxy montelukast is a key metabolite of montelukast used in pharmacokinetic and biochemical research to understand the compound′s metabolic pathways, particularly involving the cytochrome P450 enzyme family. It serves as a vital reference standard in the development of analytical methods for the quantification of montelukast and its metabolites in biological matrices, aiding in the assessment of the compound′s absorption, distribution, metabolism, and excretion characteristics. Studies involving α-Hydroxy montelukast also provide insights into potential multi-chemical interactions that could influence montelukast metabolism.
α-Hydroxy montelukast (CAS 2045402-27-3) References
- In Vitro Metabolism of Montelukast by Cytochrome P450s and UDP-Glucuronosyltransferases. | Cardoso, Jde O., et al. 2015. Drug Metab Dispos. 43: 1905-16. PMID: 26374173
- The mechanisms underlying montelukast's neuropsychiatric effects - new insights from a combined metabolic and multiomics approach. | Marques, CF., et al. 2022. Life Sci. 310: 121056. PMID: 36228771
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
α-Hydroxy montelukast, 0.5 mg | sc-489094 | 0.5 mg | $638.00 |