Adenovirus Antibody (DV4-1A): sc-65652

Adenovirus Antibody (DV4-1A) is a mouse monoclonal IgG1 antibody that detects the Adenovirus protein of Adenovirus type 2 origin by immunofluorescence (IF). Anti-Adenovirus antibody (DV4-1A) is available as the non-conjugated format. Adenoviruses are non-enveloped icosahedral viruses belonging to the family Adenoviridae, characterized by double-stranded, linear, non-segmented DNA genome. The Adenovirus structure allows for efficient infection and replication within host cells; the icosahedral shape provides stability and protection for the viral genome, facilitating delivery into host cells. The viral capsid contains 252 protein subunits, which enable attachment to and penetration of host cells, initiating the infection process. Understanding Adenovirus structural integrity is essential for developing targeted antiviral therapies and vaccines, as this knowledge can inform strategies to disrupt viral lifecycle. Adenovirus infection in humans typically manifests as respiratory illness, but depending on the serotype, can also lead to gastroenteritis, conjunctivitis, cystitis, and rash. With approximately 47 different Adenovirus types identified, and about half associated with human diseases, infants and children are particularly vulnerable to these infections.

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Adenovirus Antibody (DV4-1A) References:

1. Relaxed template specificity in fowl adenovirus 1 DNA replication initiation.  |  Rademaker, HJ., et al. 2006. J Gen Virol. 87: 553-562. PMID: 16476976
2. Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase.  |  Tsai, LH., et al. 1991. Nature. 353: 174-7. PMID: 1653904
3. Cell cycle regulation of histone H1 kinase activity associated with the adenoviral protein E1A.  |  Giordano, A., et al. 1991. Science. 253: 1271-5. PMID: 1653969
4. Equine adenovirus 1 infection of hospitalised and healthy foals and horses.  |  Bell, SA., et al. 2006. Equine Vet J. 38: 379-81. PMID: 16866210
5. An adenovirus type 5 early gene function regulates expression of other early viral genes.  |  Jones, N. and Shenk, T. 1979. Proc Natl Acad Sci U S A. 76: 3665-9. PMID: 291030
6. Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product.  |  Whyte, P., et al. 1988. Nature. 334: 124-9. PMID: 2968522
7. Monoclonal antibodies specific for adenovirus early region 1A proteins: extensive heterogeneity in early region 1A products.  |  Harlow, E., et al. 1985. J Virol. 55: 533-46. PMID: 3894685
8. Viral DNA in transformed cells. II. A study of the sequences of adenovirus 2 DNA IN NINE LINES OF TRANSFORMED RAT CELLS USING SPECIFIC FRAGMENTS OF THE VIRAL GENOME;  |  Gallimore, PH. 1974. J Mol Biol. 89: 49-72. PMID: 4613857
9. Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs.  |  Berk, AJ., et al. 1979. Cell. 17: 935-44. PMID: 487437

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Adenovirus Antibody (DV4-1A) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Adenovirus Antibody (DV4-1A) Specifications

Alternate Product Name: Adenovirus

Product Clone Name: DV4-1A

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Adenovirus

Epitope Species: Adenovirus type 2

Product Reactivity/Detection:

Species Reactivity/Detection: Adenovirus type 2

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Adenovirus Antibody (DV4-1A): N/A